Table 2.
Mixed MANCOVA Results for CT and LGI Averages per Hemisphere.a
| SZ (n = 34) | HC (n = 23) | Left | Right | |||||
|---|---|---|---|---|---|---|---|---|
| Baseline | Week 6 | Baseline | Week 6 | |||||
| M (SD) | M (SD) | M (SD) | M (SD) | F | P | F | P | |
| CT | ||||||||
| Left hemisphere | 2.435 (0.120) | 2.469 (0.113) | 2.514 (0.119) | 2.519 (0.108) | — | — | — | — |
| Right hemisphere | 2.432 (0.120) | 2.466 (0.120) | 2.507 (0.119) | 2.507 (0.112) | — | — | — | — |
| Group | — | — | — | — | 4.918 | 0.031 | 3.879 | 0.054 |
| Time | — | — | — | — | 0.079 | 0.780 | 0.020 | 0.887 |
| Time × Group | — | — | — | — | 1.067 | 0.306 | 1.741 | 0.193 |
| LGI | ||||||||
| Left hemisphere | 2.946 (0.105) | 2.940 (0.101) | 3.072 (0.156) | 3.065 (0.148) | — | — | — | — |
| Right hemisphere | 2.958 (0.111) | 2.956 (0.112) | 3.077 (0.146) | 3.073 (0.148) | — | — | — | — |
| Group | — | — | — | — | 15.542 | <0.001 | 15.619 | <0.001 |
| Time | — | — | — | — | 1.205 | 0.277 | 1.798 | 0.186 |
| Time × Group | — | — | — | — | 0.079 | 0.780 | 0.075 | 0.786 |
Note. CT = cortical thickness; HC = healthy controls; LGI = local gyrification index; M = mean; SD = standard deviation; SZ = patients with schizophrenia.
a Covariates accounted for include: age and estimated total intracranial volume. Repeated measures interactions and between subjects effects not included.