Table 2.

List of antibiotic resistance genes retrieved from the Han River virome contigs

Contig (ORF)a	ARG classification	ARG	% ident.	e value	Query cov. (%)
H6-C148-ORF17	Antibiotic inactivation	VatA	27.39	1.93 × 10−6	66
H7-C136-ORF18	Antibiotic inactivation	VatA	27.39	1.93 × 10−6	66
N1-C442-ORF2	Antibiotic inactivation	VatB	40.91	2.42 × 10−43	95
H6-C980-ORF4	Antibiotic inactivation	AAC(6’)-Is	29.41	7.38 × 10−7	72
H4-C737-ORF5	Antibiotic inactivation	AAC(6’)-Is	29.41	7.38 × 10−7	72
N3-C281-ORF7	Antibiotic inactivation	AAC(6’)-Iu	30.39	8.87 × 10−7	72
N3-C510-ORF10	Antibiotic inactivation	AAC(6’)-Iu	31.37	8.66 × 10−8	72
N1-C181-ORF5	Antibiotic inactivation	AAC(6’)-Iu	30.39	8.87 × 10−7	72
H6-C750-ORF4	Antibiotic inactivation	AAC(6’)-Iu	31.37	9.12 × 10−8	72
H1-C452-ORF7	Antibiotic inactivation	AAC(6’)-Iu	30.39	8.87 × 10−7	72
N3-C559-ORF4	Antibiotic inactivation	AAC(6’)-Iy	20.42	5.52 × 10−5	84
H4-C798-ORF18	Antibiotic inactivation	AAC(6’)-Iy	20.42	5.52 × 10−5	84
H7-C307-ORF22	Antibiotic inactivation	AAC(6’)-Iy	20.42	5.52 × 10−5	84
H1-C107-ORF42	Antibiotic inactivation	AAC(6’)-Iy	20.42	5.52 × 10−5	84
H4-C441-ORF28b	Antibiotic inactivation	β-lactamase	37.18	8.00 × 10−38	88
H4-C244-ORF21b	Antibiotic inactivation	β-lactamase	37.45	1.00 × 10−57	96
H4-C367-ORF18b	Antibiotic inactivation	β-lactamase	37.45	1.00 × 10−57	96
H1-C74-ORF21b	Antibiotic inactivation	β-lactamase	37.45	1.00 × 10−57	96
H1-C267-ORF1	Antibiotic target protection	QnrA3	28.78	8.13 × 10−5	65
H6-C122-ORF31	Antibiotic target alteration	DfrB2	67.31	6.88 × 10−21	83
H4-C9-ORF60	Antibiotic target alteration	DfrB2	67.31	6.88 × 10−21	83
H7-C8-ORF44	Antibiotic target alteration	DfrB2	67.31	6.88 × 10−21	83
H1-C119-ORF31	Antibiotic target alteration	DfrB2	67.31	6.88 × 1021	83
H6-C515-ORF10	Antibiotic target alteration	VanY	27.10	1.02 × 10−5	76
H4-C770-ORF17	Antibiotic target alteration	VanY	27.10	1.02 × 10−5	76

^aContig number (C) and ORF number (ORF) are listed after study site number

^bThe % identity, e value, and query coverage of β-lactamases have been retrieved from BLASTp against NCBI nr database