Table 1.

Testing of alternative topologies.

Alternative topologya	Switched branches	LogLb	∆Lc	P valued
1	Italy with Wales	–45443.2	0.0000	.24
2	Germany with Brazil	–45451.5	8.3554	.16
3	Portugal with Brazil	–45443.2	0.0002	.75
4	Germany with Portugal	–45451.5	8.3197	.16

^aAlternative topologies were obtained by switching branches in the maximum likelihood tree inferred from SARS-CoV-2 full genome sequences. 1) Italy (EPI_ISL_412973) switched with Wales (EPI_ISL_413555); 2) Germany (EPI_ISL_406862) with Brazil (EPI_ISL_412964); 3) Portugal (EPI_ISL_413648) with Brazil (EPI_ISL_412964); 4) Germany (EPI_ISL_406862) with Portugal (EPI_ISL_413648).

^bLogL: log likelihood estimated for each alternative topology.

^c∆L: difference between LogL and the log likelihood of the original tree.

^dCalculated with the Shimodaira-Hasegawa test [32].