Fig. 2: superposing of main proteinase (Mpro) (domains I and II) with thrombin (A) and factor Xa (B). C and D highlights the similarity of docked results and crystallography structures. C- Docked Argatroban (blue) compared to the experimentally solved (purple, PDB code 4HFP) structure complexed to thrombin. D- Apixaban docked with factor Xa (red) and its crystallography structure (green, PDB code 2P16).
