Table 1:
Description of the AGES study population (N = 5457, 57% females), stratified on ACEIs and ARBs use
| Characteristic | ACEIs | ARBs | ACEIs and/or ARBs | Total | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| No n=3972 |
Yes n=699 |
No n=3972 |
Yes n=753 |
No n=3972 |
Yes n=1485 |
N=5457 | ||||
| Age, years (SD) | 76.6 (5.6) | 76.9 (5.7) | ns | 76.6 (5.6) | 76.4 (5.4) | ns | 76.6 (5.6) | 76.7 (5.5) | ns | 76.6 (5.6) |
| BMI (kg/m2), mean (SD) | 26.6 (4.3) | 27.8 (4.5) | *** | 26.6 (4.3) | 28.5 (4.5) | *** | 26.6 (4.3) | 28.1 (4.5) | *** | 27.1 (4.4) |
| BMI>30, n (%) | 777 (19.6%) | 197 (28.2%) | *** | 777 (19.6%) | 235 (31.3%) | *** | 777 (19.6%) | 439 (29.6%) | *** | 1216 (22.3%) |
| Hypertension - measured onlya, n (%) | 1843 (46.4%) | 426 (60.9%) | *** | 1843 (46.4%) | 449 (59.6%) | *** | 1843 (46.4%) | 896 (60.3%) | *** | 2739 (50.2%) |
| Hypertensionb, n (%) | 2934 (73.9%) | 699 (100.0%) | - | 2934 (73.9%) | 753 (100.0%) | ns | 2934 (73.9%) | 1485 (100.0%) | - | 4419 (81.0%) |
| Type II diabetes, n (%) | 358 (9.0%) | 160 (22.9%) | *** | 358 (9.0%) | 131 (17.4%) | *** | 358 (9.0%) | 300 (20.2%) | *** | 658 (12.1%) |
| Current smoking, n (%) | 516 (13.4%) | 72 (10.6%) | * | 516 (13.4%) | 65 (8.8%) | ** | 516 (13.4%) | 139 (9.6%) | *** | 655 (12.3%) |
a
Hypertension according to measurements only, systolic blood pressure>140 or diastolic blood pressure>90 mmHg
b
Hypertension according to measurements, medications and questionnaire ns: not significant
*
P-value<0.05
**
P-value < 0.01
***
P-value <0.001
P-values from two tailed T-tests for continuous variables, Chi-square test for categorical variables