Fig. 1.

FGF gene and protein expression in kidneys with AKI. a, b Quantitative real-time PCR analysis showing the altered expression of FGF mRNA in kidneys from mice after IR (a) and cisplatin injection (b). * p < 0.05 vs. sham or vehicle control, n = 3–8. c Representative micrographs of immunohistochemistry staining revealing increased FGF2, FGF7, and FGF10 protein expression in renal tubules after IR. d–g Western blot and quantitative analysis demonstrating that FGF2, FGF7, and FGF10 protein expression was induced in IR kidneys (d, e) and FGF2 protein expression in mice after cisplatin injection (f, g). * p < 0.05 vs. sham or vehicle control, n = 3.