Fig. 7.

Erk1/2 phosphorylation is diminished in the kidneys from Tubule-FGFR2^−/− mice after cisplatin injection. a Representative micrographs showing the immunohistochemical staining images for p-Erk1/2 at day 1 after cisplatin injection. b Western blot analysis showing the induction of Erk1/2 phosphorylation in the kidneys from Tubule-FGFR2^−/− or control littermates at different time points after cisplatin injection. c Graph showing the semiquantitative result for p-Erk1/2. * p < 0.05 vs. control littermates, n = 3–4. d Western blot assay for the p-Bad at day 1 after cisplatin injection. e Graph showing the semiquantitative result for p-Bad in the kidneys from Tubule-FGFR2^−/− and control littermates. * p < 0.05 vs. control littermates, n = 4. The number indicates the individual animal.