Table 3.

Adjusted analyses on differences in pulse wave velocity (PWV), blood pressure and augmentations index (Aix) in patients newly diagnosed with Graves' disease (GD) versus euthyroid controls (reference)

GD vs. controls	Mean difference between groups (95% CI)	p value
Office measurements
PWV, m/sa	−0.2 (−0.6 to 0.3)	0.49
Aix, %c	4.3 (−0.6 to 9.2)	0.09
Brachial measurements
SBP, mm Hgb	2.8 (−2.2 to 7.8)	0.27
DBP, mm Hgb	−1.6 (−5.1 to 2.0)	0.38
PP, mm Hgb	4.3 (1.1 to 7.6)	0.01
MAP, mm Hgb	−0.1 (−3.9 to 3.6)	0.95
Central measurements
SBP, mm Hgb	1.5 (−3.2 to 6.1)	0.54
DBP, mm Hgb	−1.7 (−5.2 to 1.9)	0.36
PP, mm Hgb	3.1 (0.5 to 5.8)	0.02
MAP, mm Hgb	0.3 (−3.7 to 4.2)	0.90
24-h measurements
PWV, m/sa	1.0 (0.6 to 1.5)	<0.001
Aix, %c	−1.3 (−4.9 to 2.2)	0.46
Brachial measurements
SBP, mm Hgb	1.6 (−4.5 to 7.7)	0.60
DBP, mm Hgb	−3.0 (−7.0 to 1.0)	0.14
PP, mm Hgb	4.6 (0.8 to 8.4)	0.02
MAP, mm Hgb	−1.5 (−6.0 to 3.0)	0.51
Central measurements
SBP, mm Hgb	1.1 (−6.3 to 8.5)	0.77
PP, mm Hgb	4.8 (0.7 to 8.9)	0.02
MAP, mm Hgb	−2.1 (−7.4 to 3.2)	0.43

SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial blood pressure; PP, pulse pressure; Aix, augmentation index.

^aAdjusted for age, sex, heart rate (office or 24 h), MAP and smoking.

^bAdjusted for age, sex, body mass index, heart rate (office or 24 h) and smoking.

^cAdjusted for age, sex, heart rate (office or 24 h), height and smoking.