Table 4.

Adjusted analyses of differences in nightly dipping and day- and night-time blood pressure, pulse wave velocity and wave reflection in patients newly diagnosed with Graves' disease (GD) compared to euthyroid controls (reference)

33GD vs. controls	Difference between groups (95% CI)	p value
Daytime
PWV, m/sa	1.0 (0.5 to 1.4)	<0.001
PP, mm Hgb	3.8 (−0.0 to 7.6)	0.05
SBP, mm Hgb	0.5 (−5.9 to 6.8)	0.88
DBP, mm Hgb	−3.3 (−7.6 to 1.0)	0.13
Aix, %c	−2.3 (−5.7 to 1.1)	0.19
Central PP, mm Hgb	3.3 (−0.8 to 7.4)	0.12
Night-time
PWV, m/sa	1.2 (0.7 to 1.8)	<0.001
PP, mm Hgb	5.5 (1.5 to 9.4)	<0.01
SBP mm Hgb	4.1 (−2.4 to 10.6)	0.21
DBPb, mm Hgb	−1.3 (−5.6 to 2.9)	0.53
Aix, %c	1.2 (−3.2 to 5.5)	0.59
Central PP, mm Hgb	6.9 (2.6 to 11.3)	<0.01
Night-time dipping
PWV, %d	−5.5 (−10.4 to 0.6)	0.03
HR, %e	−3.4 (0.1 to 6.8)	0.04
SBP, %f	−1.9 (−5.4 to 1.5)	0.27
DBP, %f	−1.8 (−6.4 to 2.7)	0.43
PP, %f	−0.5 (−4.6 to 3.6)	0.82
Central SBP, %f	−3.5 (−7.7 to 0.6)	0.09
Central PP, %f	−5.4 (−10.5 to 0.2)	0.04

PWV, pulse wave velocity; SBP, brachial systolic blood pressure; MAP, brachial mean arterial blood pressure; PP, brachial pulse pressure; Aix, augmentation index; HR, heart rate.

^aAdjusted for age, sex, heart rate (office or 24 h), MAP and smoking.

^bAdjusted for age, sex, heart rate (office or 24 h), BMI and smoking.

^cAdjusted for age, sex, heart rate (office or 24 h), height and smoking.

^dAdjusted for age, sex, and night-time mean heart rate, MAP and smoking.

^eAdjusted for age and sex.

^fAdjusted for age, sex, mean night-time heart rate, BMI and smoking.