Table 1.
Summary of common lymphatic markers
Marker | Cellular sites of expression | Molecular function |
---|---|---|
VEGFR-3 | Cell membrane | Tyrosine kinase receptor |
Lyve-1 | Cell membrane | Hyaluronan receptor |
Prox-1 | Cell nucleus | Transcription factor |
Podoplanin | Cell membrane | Transmembrane glycoprotein |
CCL21 | CC-chemokine for CCR7+ cells |