Table 3.
Diagnostic value of 8 estimating equations compared with rGFR
| R | p value | ROCAUC | Sensitivity | Specificity | |
|---|---|---|---|---|---|
| B2M GFR | 0.626 | <0.001 | 0.829 | 73.7 | 74.1 |
| CKD-EPIscr | 0.774 | <0.001 | 0.870 | 76.2 | 82.6 |
| CKD-EPIcys | 0.722 | <0.001 | 0.837 | 76.0 | 74.1 |
| CKD-EPIscr-cys | 0.778 | <0.001 | 0.867 | 76.0 | 81.2 |
| C-CKD-EPIscr | 0.774 | <0.001 | 0.870 | 83.3 | 71.5 |
| C-CKD-EPIcys | 0.722 | <0.001 | 0.837 | 82.7 | 64.1 |
| C-CKD-EPIscr-cys | 0.778 | <0.001 | 0.867 | 82.9 | 71.2 |
| Xiangya GFR | 0.774 | <0.001 | 0.869 | 71.2 | 89.5 |
R, coefficient of relationship between eGFR and rGFR by Pearson correlation analysis; ROCAUC, area under the receiver operating characteristic curve; B2M GFR, beta-2 microglobulin-based equation; CKD-EPIscr, serum creatinine-based CKD-EPI equation which was developed in 2009; CKD-EPIcys, cystatin C-based CKD-EPI equation which was developed in 2012; CKD-EPIscr-cys, serum creatinine and cystatin C-based CKD-EPI equation which was developed in 2012; C-CKD-EPIscr, CKD-EPIscr equation modified for China which was newly developed in 2019; C-CKD-EPIcys, CKD-EPIcys equation modified for China which was newly developed in 2019; C-CKD-EPIscr-cys, CKD-EPIscr-cys equation modified for China which was newly developed in 2019; Xiangya GFR, serum creatinine-based equation which was newly developed in the Third Xiangya Hospital in China in 2019. Correlation coefficients of estimating equation were compared with rGFR.