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. 2020 Mar 25;98(5):315–329. doi: 10.2471/BLT.19.237149

Table 5. Global and regional estimates of the incidence of herpes simplex virus type 1 infection (at any site) by age and sex, 2016.

WHO region by sex No. of infected people in millions (population incidence, %) by age
95% UIa
0–4 years 5–9 years 10–14 years 15–19 years 20–24 years 25–29 years 30–34 years 35–39 years 40–44 years 45–49 years Total
Total 81.4 (12.3) 19.1 (3.0) 7.0 (1.2) 3.8 (0.7) 2.7 (0.5) 2.1 (0.3) 1.5 (0.3) 1.2 (0.2) 0.9 (0.2) 0.7 (0.2) 120.4 (2.1) 114.3–130.1 (2.0–2.3)
Female
Africa 16.7 (21.4) 1.6 (2.4) 0.2 (0.3) < 0.1b (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) 18.5 (4.2) 16.1–22.0 (3.6–5.0)
Americas 1.0 (3.0) 0.9 (2.5) 0.8 (2.1) 0.7 (1.8) 0.6 (1.6) 0.5 (1.3) 0.4 (1.1) 0.3 (1.0) 0.3 (0.8) 0.2 (0.7) 5.6 (1.6) 5.4–5.8 (1.5–1.7)
Eastern Mediterranean 3.1 (7.8) 1.7 (4.7) 0.9 (2.8) 0.5 (1.7) 0.3 (1.0) 0.2 (0.6) 0.1 (0.4) < 0.1b (0.2) < 0.1b (0.1) < 0.1b (0.1) 6.8 (2.5) 5.3–8.0 (1.9–2.9)
Europe 1.7 (6.5) 1.1 (4.2) 0.7 (2.7) 0.4 (1.7) 0.3 (1.1) 0.2 (0.7) 0.2 (0.5) 0.1 (0.3) 0.1 (0.2) < 0.1b (0.1) 4.8 (1.7) 4.4–5.0 (1.5–1.8)
South-East Asia 10.5 (12.7) 2.2 (2.5) 0.4 (0.5) 0.1 (0.1) < 0.1b (0.0) < 0.1b (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) 13.2 (1.7) 12.6–14.2 (1.7–1.9)
Western Pacific 7.0 (12.3) 2.3 (4.2) 0.7 (1.4) 0.3 (0.5) 0.1 (0.2) < 0.1b (0.1) < 0.1b (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) 10.5 (1.6) 9.8–13.1 (1.5–2.0)
Total 40.0 (12.6) 9.8 (3.2) 3.7 (1.3) 2.0 (0.7) 1.3 (0.5) 0.9 (0.3) 0.7 (0.2) 0.5 (0.2) 0.3 (0.1) 0.3 (0.1) 59.4 (2.2) 56.3–63.9 (2.0–2.3)
Male
Africa 17.2 (21.4) 1.7 (2.4) 0.2 (0.3) < 0.1b (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) 19.0 (4.3) 16.5–22.6 (3.7–5.1)
Americas 0.9 (2.4) 0.8 (2.1) 0.7 (1.9) 0.6 (1.6) 0.6 (1.4) 0.5 (1.3) 0.4 (1.1) 0.3 (1.0) 0.3 (0.9) 0.2 (0.8) 5.2 (1.5) 4.9–5.5 (1.4–1.6)
Eastern Mediterranean 3.3 (7.8) 1.8 (4.7) 0.9 (2.8) 0.5 (1.7) 0.3 (1.0) 0.2 (0.6) 0.1 (0.4) 0.1 (0.2) < 0.1b (0.1) < 0.1b (0.1) 7.2 (2.4) 5.7–8.4 (1.9–2.9)
Europe 0.9 (3.1) 0.7 (2.6) 0.6 (2.2) 0.5 (1.9) 0.5 (1.6) 0.4 (1.4) 0.4 (1.1) 0.3 (1.0) 0.3 (0.8) 0.2 (0.7) 4.7 (1.6) 4.3–5.1 (1.5–1.7)
South-East Asia 11.4 (12.7) 2.4 (2.5) 0.5 (0.5) 0.1 (0.1) < 0.1b (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) 14.4 (1.8) 13.8–15.5 (1.7–1.9)
Western Pacific 7.7 (12.0) 2.0 (3.2) 0.5 (0.9) 0.1 (0.2) < 0.1b (0.1) < 0.1b (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) < 0.1c (0.0) 10.5 (1.5) 9.4–15.5 (1.3–2.2)
Total 41.3 (12.1) 9.3 (2.8) 3.4 (1.1) 1.9 (0.6) 1.4 (0.5) 1.1 (0.4) 0.9 (0.3) 0.7 (0.3) 0.5 (0.2) 0.4 (0.2) 61.0 (2.1) 57.6–66.8 (2.0–2.3)

UI: uncertainty interval; WHO: World Health Organization.

a 95% UI of the total no. of infected people in millions (95% UI of percentage incidence).

b Numbers are < 50 000 ≥ 10 000.

c Numbers are < 10 000.

Notes: Numbers are the estimated number of people newly infected with herpes simplex virus type 1 during 2016. Incidences are the percentage of infected people in the age- sex- and region-specific population. Incidence values of < 0.05% are rounded to 0.0%. Numbers do not always sum exactly to the totals due to rounding. Regions are World Health Organization definitions.