TABLE 2.
Proteins Significantly Increased in Post-Shock Mesenteric Lymph Exosomes Compared to Pre-Shock
| Protein | UniProt ID | Fold Increase |
p Value |
Adjusted p Value |
|
|---|---|---|---|---|---|
| Major urinary protein | P02761 | 78.2 | 0.035 | 0.062 | a,c |
| Procollagen type XVIII alpha 1 | F1LR02 | 55.7 | 0.045 | 0.076 | |
| Hephaestin | Q920H8 | 41.7 | 0.029 | 0.045 | a |
| Laminin C1 | F1MAA7 | 39.0 | 0.018 | 0.045 | |
| Thrombospondin 1 | A0A0G2JV24 | 26.4 | 0.100 | 0.045 | |
| Cofilin-1 | P45592 | 21.4 | 0.031 | 0.071 | a,b |
| Coronin-1A | Q91ZN1 | 20.0 | 0.010 | 0.032 | |
| Desmoglein 2 | F1LYX9 | 18.0 | 0.006 | 0.020 | b |
| von Willebrand factor (Fragment) | Q62935 | 15.5 | 0.033 | 0.062 | |
| Ribonuclease 4 | O55004 | 15.1 | 0.006 | 0.026 | a |
| Thymosin beta-4 | P62329 | 14.9 | 0.011 | 0.005 | a |
| Fructose-bisphosphate aldolase A | P05065 | 14.2 | 0.006 | 0.005 | a,b |
| Collagen alpha-2(I) chain | P02466 | 13.0 | 0.003 | 0.020 | |
| Heat shock cognate 71 kDa | P63018 | 12.9 | <0.001 | 0.005 | a,b |
| Actin, cytoplasmic 1 | P60711 | 11.3 | 0.008 | 0.031 | a,b,c |
| Prosaposin | P10960 | 10.8 | 0.003 | 0.005 | a |
| Profilin-1 | P62963 | 9.4 | 0.003 | 0.005 | a,b |
| Desmocolin 2 | D3ZJR7 | 9.1 | 0.016 | 0.045 | |
| Insulin-like growth factor-binding protein 4 | P21744 | 8.6 | 0.027 | 0.020 | a |
| Fructose-bisphosphate aldolase B | P00884 | 8.1 | 0.011 | 0.035 | a,b |
| Glycogen phosphorylase, muscle form | P09812 | 7.7 | 0.046 | 0.031 | a,b |
| 72 kDa type IV collagenase | P33436 | 7.6 | 0.029 | 0.020 | a |
| L-lactate dehydrogenase A chain | P04642 | 7.5 | 0.026 | 0.062 | a,b |
| Lysozyme C-1 | P00697 | 7.1 | 0.021 | 0.031 | a,b |
| Glyceraldehyde-3-phosphate dehydrogenase | MOR660 | 7.0 | 0.009 | 0.026 | a |
| Lumican | P51886 | 6.7 | 0.047 | 0.076 | a,b |
| Periostin osteoblast specific factor | D3ZAF5 | 6.3 | 0.007 | 0.020 | |
| Procollagen C-endopeptidase enhancer 1 | O08628 | 6.2 | 0.004 | 0.020 | |
| Urinary protein 1-like | D3ZIF6 | 6.2 | 0.005 | 0.020 | |
| Parvalbumin alpha | P02625 | 6.1 | 0.042 | 0.076 | a,c |
| Fibulin-5 | Q9WVH8 | 5.2 | 0.004 | 0.020 | |
| Cystatin-C | P14841 | 4.6 | 0.043 | 0.077 | a,b |
| Carbonic anhydrase 3 | P14141 | 4.0 | 0.014 | 0.026 | a,b,c |
| Fibulin-1 | D3ZQ25 | 3.4 | 0.037 | 0.020 | |
| Ficolin-1 | Q9WTS8 | 3.2 | 0.045 | 0.026 |
a =
Also increased in D’Allesandro et al Shock 2014; 42(6): 509–517
b =
Also increased in Mittal et al Shock 2010; 32(2):140-9
c =
Also increased in Peltz et al Surgery 2009; 146(2):347-57