FIGURE 2.

Echocardiography was used to evaluate cardiac function. Latifolin significantly improved cardiac function, and LVEF and LVFS were increased significantly. A, Normal heart function of control group; (B) DOX decreased cardiac systolic function; (C) low-dose latifolin (50 mg/kg) group; (D) high-dose latifolin (100 mg/kg) group; (E) left ventricular systolic diameter result; (F) left ventricular diastolic diameter result. (G) left ventricular ejection fraction result; (H) left ventricular fractional shortening result. Data were shown as mean ± SD, n = 8. ##P < 0.01 versus control group, **P < 0.01 versus DOX group.