Table 1.
Clinical and metabolic characteristics in African American (AA) and non-Hispanic White (NHW) subjects.
NHW (n = 18) | AA (n = 18) | P value | |
---|---|---|---|
Age (years) | 39.5 ± 10.9 | 37.9 ± 12.4 | .65 |
Sex (female, n) | 9 | 6 | .49 |
Body mass index (kg/m2) | 28.7 ± 6.9 | 27.8 ± 6.8 | .66 |
Total body fat (%) | 32.8 ± 13.4 | 27.3 ± 11.2 | .22 |
Total body fat (kg) | 29.4 ± 17.4 | 24.8 ± 14.3 | .53 |
Fat-free mass (kg) | 55.0 ± 95.2 | 62.9 ± 12.2 | .06 |
Visceral adipose tissue (g) | 979 ± 800 | 963 ± 724 | .96 |
Fasting plasma glucose (mg/dL) | 90 ± 8 | 92 ± 10 | .12 |
Fasting plasma insulin (mU/L) | 8.5 ± 5.6 | 7.8 ± 5.6 | .09 |
Hemoglobin A1C (%) | 5.3 ± 0.4 | 5.8 ± 0.3 | .001 |
Total cholesterol (mg/dL) | 173 ± 37 | 177 ± 29 | .38 |
LDL cholesterol (mg/dL) | 90 ± 39 | 100 ± 22 | .09 |
HDL cholesterol (mg/dL) | 64 ± 21 | 61 ± 10 | .98 |
Triglycerides (mg/dL) | 97 ± 43 | 79 ± 36 | .20 |
Free fatty acid (mEq/L) | 0.44 ± 0.18 | 0.33 ± 0.15 | .07 |
Glucose disposal rate (M) (mg/kgFFM +17.7/min) | 12.6 ± 4.2 | 12.6 ± 3.2 | .49 |
QUICKI | 0.36 ± 0.03 | 0.35 ± 0.04 | .81 |
Basal HGP (mg/kg/min) | 2.54 ± 0.31 | 2.49 ± 0.34 | .64 |
Hepatic insulin resistance index (mg/kg/min.ng/mL) | 6.40 ± 3.88 | 7.24 ± 3.33 | .38 |
Data are presented as arithmetic mean ± SD; P values indicate significance for comparisons between ethnic groups.
Abbreviations: n, no. of subjects. QUICKI, quantitative insulin sensitivity check index; HGP, hepatic glucose production.