Table 2.
Measures of insulin sensitivity and β-cell function in African American (AA) and non-Hispanic White (NHW) subjects.
| NHW (n=18) (F/M, 6/12) | AA (n=18) (F/M, 9/9) | P value | |
|---|---|---|---|
| Glucose disposal rate (M) (mg/kgFFM +17.7/min) | 12.6 ± 4.2 | 12.6 ± 3.2 | .49 |
| Females (F) | 12.4 ± 4.9 | 15.1 ± 1.8 | .08 |
| Males (M) | 12.8 ± 3.7 | 11.3 ± 3.1 | .55 |
| P value | .45 | .02 | |
| Hepatic insulin resistance index (mg/kg/min x ng/mL) | 6.40 ± 3.88 | 7.24 ± 3.33 | .38 |
| Females | 6.89 ± 3.83 | 5.79 ± 1.01 | 1.00 |
| Males | 6.09 ± 4.14 | 8.27 ± 4.08 | .27 |
| P value | .71 | .32 | |
| Acute insulin response (µU/mL/min) | 340 ± 177 | 910 ± 667 | .03 |
| Females | 358 ± 186 | 1095 ± 286 | .002 |
| Males | 323 ± 177 | 818 ± 788 | .37 |
| P value | .54 | .22 | |
| X0 (nmol/min/L) | 1.81 ± 0.75 | 4.42 ± 2.44 | .007 |
| Females | 1.62 ± 0.81 | 6.39 ± 1.91 | .002 |
| Males | 1.99 ± 0.67 | 3.35 ± 2.03 | .19 |
| P value | .25 | .02 | |
| Φ Basal (109/min) | 8.08 ± 3.34 | 8.05 ± 2.49 | .89 |
| Females | 9.00 ± 3.89 | 8.39 ± 2.83 | .77 |
| Males | 7.16 ± 2.59 | 7.87 ± 2.42 | .50 |
| P value | .33 | 1.00 | |
| Φ 1 (109) | 194 ± 112 | 377 ± 250 | .03 |
| Females | 150 ± 65 | 629 ± 178 | .002 |
| Males | 238 ± 135 | 251 ± 174 | 1.00 |
| P value | .09 | .003 | |
| Φ 2 (109/min) | 10.39 ± 4.37 | 7.48 ± 6.73 | .12 |
| Females | 11.67 ± 4.87 | 6.98 ± 9.72 | .17 |
| Males | 9.11 ± 3.64 | 7.73 ± 5.19 | .64 |
| P value | .33 | .39 | |
| Φ Total (109/min) | 29.6 ± 19.8 | 76.7 ± 75.3 | .03 |
| Females | 20.4 ± 8.63 | 106.7 ± 93.1 | .002 |
| Males | 38.8 ± 23.9 | 60.4 ± 62.5 | .88 |
| P value | .03 | .13 |
Data are presented as arithmetic mean ± SD; n, no. of subjects. P values indicate significance for comparisons between ethnic groups or between sexes.