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. 2020 May 24;26:e923688-1–e923688-14. doi: 10.12659/MSM.923688

Figure 4.

Figure 4

The inhibition effects of the PGC-1α/SIRT3 pathway on brain injury after SAH. (A, B) The changes of MDA and SOD in different groups after LV-shPGC-1α administration in vivo. (C, D) The number of apoptotic neurons of cortex in different groups at 24 h post-SAH. (E) The neurologic scores of mice in different groups at 24 h post-SAH. (F) The spatial learning ability of mice in different groups after SAH: spatial reversal was performed on day 4 after SAH. (**** P<0.001, ** P<0.01, * P<0.05; n=6/group; Scale bar=25 μm).