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Comparison of time-dependent growth curves of E. coli MG1655 strains expressing the metallo-β-lactamase NDM-1 vs. the serine β-lactamase CTX-M-1 in the presence of varying concentrations of PcephPT and PT, illustrating the delayed antibacterial activity of PcephPT in the NDM-1-expressing strain. Growth in Mueller Hinton media at 37 °C was assessed by measuring OD600 every 30 minutes.
