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. 2020 Mar 27;152(6):e201912506. doi: 10.1085/jgp.201912506

Table 1. Parameters for Scheme 1, fitted with data at 0 µM NS11021.

Parameter Fit A Fit B
J0 0.08 0.06
KD (µM) 41 17
L0 2.8 × 10−6 1.0 × 10−5
zJ (e0) 0.30 0.41
zL (e0) 0.57 0.58
C 2.5 17
D 29 16
E 20 1.1

Simultaneous (global) fitting was performed using G–V relations over a range of Ca2+ with 0 µM NS11021, as described in Materials and methods. G–V relations predicted by above parameters in Fit A and Fit B can be found in Figs. 7 A and 8 A, respectively. χ2 values for comparison of experimental data versus corresponding prediction (based on 90 experimental data points): Fit A, 0.045; Fit B, 0.044.