. 2017 Jun 1;2017:192, Part 1.

Table 24.

Descriptive Statistics of Lung Function, Airway Injury, and Airway Inflammation

Outcome	0 ppb			70 ppb			120 ppb
Outcome	N	Mean	SD	N	Mean	SD	N	Mean	SD
FEV₁ (L)
Pre-exposure	87	2.946	0.632	87	2.949	0.620	87	2.962	0.637
15-min Post-exposure	87	3.031	0.650	87	3.027	0.638	86	3.011	0.646
22-hr Post-exposure	87	2.991	0.634	87	2.971	0.621	87	2.965	0.635
FVC (L)
Pre-exposure	87	3.904	0.872	87	3.904	0.867	87	3.912	0.870
15-min Post-exposure	87	3.978	0.894	87	3.968	0.886	86	3.939	0.871
22-hr Post-exposure	87	3.930	0.877	87	3.899	0.851	87	3.891	0.866
FEV₁/FVC (%)
Pre-exposure	87	75.74	4.76	87	75.80	4.89	87	75.99	4.84
15-min Post-exposure	87	76.51	4.66	87	76.57	4.71	86	76.67	4.51
22-hr Post-exposure	87	76.40	4.87	87	76.40	4.37	87	76.50	4.56
FEF_25–75 (L/sec)
Pre-exposure	87	2.481	0.781	87	2.508	0.790	87	2.527	0.812
15-min Post-exposure	87	2.657	0.782	87	2.678	0.836	86	2.652	0.836
22-hr Post-exposure	87	2.586	0.778	87	2.582	0.779	87	2.596	0.786
CC16 (ng/mL)^a
Pre-exposure	85	16.38	8.12	85	16.59	8.00	84	16.47	7.62
4-hr Post-exposure	85	16.69	8.10	85	17.79	7.93	84	20.46	8.80
22-hr Post-exposure	82	19.12	8.63	85	20.01	9.30	82	19.78	8.93
PMN % of total^b	61	46.8	23.7	62	50.7	22.8	62	56.2	19.3
Ln of PMN (count/mg)^b	61	6.0	2.7	61	6.5	2.2	62	6.8	1.5
Ln of IL-6 (pg/mL) ^b	77	–0.61	1.93	80	–0.44	2.04	76	–0.55	2.34
Ln of IL-8 (pg/mL) ^b	78	4.59	1.91	80	4.99	1.48	76	4.65	2.40
Ln of TNF-α (pg/mL)^b	78	–2.34	2.04	80	–2.35	2.42	76	–2.17	2.18
Ln of total protein (μg/mL)^b	77	5.62	0.90	80	5.52	1.06	76	5.39	1.03

^a Measured in plasma on the day before exposure and 4 and 22 hours post-exposure.

^b Measured in sputum 22 hours post-exposure.