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. 2019 Mar 1;2019:197.

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Health Effects Institute Research Report 197 © 2019

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Figure 6. — Correlation between reactive oxygen and nitrogen species (ROS/RNS) production and extrinsic and intrinsic AUC and PM components. Production expressed as extrinsic (per volume of air sampled) AUC in (A) through (D) and as intrinsic (per mass of PM) AUC in (E) with PM components for summer and winter (spring/autumn data in gray shown for reference). PM components are (A) water-soluble organic carbon concentration (WSOC); (B) brown carbon concentration (BrC) (Mm = megameter); (C) iron concentration (Fe); (D) titanium concentration (Ti); and (E) titanium fraction. Data points represent individual filters tested using either alveolar macrophages (MH-S, closed circles) or ventricular myocytes (NRVM, open circles). Linear regressions and Pearson correlation coefficients are shown. * indicates significance (P < 0.05). (Adapted from Tuet et al. 2016 with permission from Elsevier.)