Table 1.
Baseline Data for All Groups
| Treatment Group | Exposure | Weight (g) |
Baseline Ppi (mm H2O) |
Heart Rate (Beats/Min) |
Blood Pressure (mm Hg) | |
|---|---|---|---|---|---|---|
| Systolic | Diastolic | |||||
| Nonsensitized | Air | 351.3 ± 5.2 | 102.2 ± 4.9 | 287.8 ± 9.8 | 41.0 ± 1.1 | 19.6 ± 0.7 |
| O3 Day 1 | 383.5 ± 11.2 | 202.5* ± 4.8 | 273.8 ± 5.5 | 46.0 ± 2.1 | 20.9 ± 1.0 | |
| O3 Day 3 | 382.6 ± 11.0 | 151.4* ± 6.3 | 283.6 ± 6.0 | 44.8 ± 2.7 | 24.0 ± 1.5 | |
| Nonsensitized+Etanercept | Air | 360.5 ± 3.3 | 105.0 ± 8.6 | 272.5 ± 18.7 | 44.5 ± 1.5 | 24.5# ± 2.0 |
| O3 Day 3 | 379.6 ± 4.8 | 172.0* ± 12.4 | 272.0 ± 8.7 | 44.8 ± 1.7 | 21.6 ± 1.3 | |
| Sensitized | Air | 406.8# ± 17.4 | 102.0 ± 8.6 | 302.0 ± 9.9 | 43.5 ± 2.9 | 20.0 ± 0.8 |
| O3 Day 3 | 394.8 ± 3.0 | 158.3* ± 12.7 | 275.0* ± 4.3 | 44.3 ± 1.9 | 22.3 ± 1.6 | |
| Sensitized + Etanercept | Air | 402.7 ± 16.9 | 95.0 ± 5.0 | 275.0 ± 5.0 | 45.0 ± 1.0 | 21.5 ± 0.5 |
| O3 Day 3 | 366.5 ± 4.3 | 137.5 ± 19.7 | 277.5 ± 8.5 | 47.0 ± 3.1 | 23.0 ± 1.0 | |
* are significantly different from air control within each group and
# is significantly different from nonsensitized air controls.