Table 2. Meta-regression analyses of demographic and clinical variables in Parkinson’s disease with mild cognitive impairment patients.
| Variables/Anatomical regions | Peak MNI coordinates (x, y, z) | Number of voxels | SDM-Z value | P value |
|---|---|---|---|---|
| Age | ||||
| Left rolandic operculum | –50, 0, 4 | 1053 | –2.401 | 0.000030994 |
| PD duration | ||||
| Right inferior temporal gyrus | 56, –20, –26 | 80 | –1.415 | 0.000141382 |
| Left temporal pole, superior temporal gyrus | –30, 20, –30 | 45 | –1.518 | 0.000053644 |
| Left middle temporal gyrus | –62, –24, 2 | 15 | –1.361 | 0.000374138 |
| UPDRS-III score | ||||
| Left inferior temporal gyrus | –46, –8, –40 | 106 | –1.534 | 0.000009835 |
| Right inferior temporal gyrus | 46, –6, –40 | 39 | –1.507 | 0.000207961 |
| Left inferior frontal gyrus | –40, 34, 16 | 30 | –1.513 | 0.000163078 |
| Hoehn and Yahr stage | ||||
| Left inferior temporal gyrus | –46, –10, –36 | 88 | –1.386 | 0.000248730 |
| Right inferior temporal gyrus | 48, –10, –38 | 85 | –1.507 | 0.000128508 |
| Left inferior frontal gyrus | –40, 36, 14 | 22 | –1.318 | 0.000505269 |
| Right middle frontal gyrus | 38, 44, 12 | 17 | –1.317 | 0.000588357 |
| Education level | − | − | − | − |
| MMSE scores | − | − | − | − |
MNI: Montreal Neurological Institute; SDM: seed-based d mapping; PD: Parkinson’s disease; UPDRS-III: Unified Parkinson’s Disease Rating Scale: Part III; MMSE: mini-mental state examination.