Figure 3.

Adjusted effect measure of exposures on birth weight by offspring sex (ExWAS approach). Estimates are given as a change in mean birth weight (g) for each inter-quartile range (defined over all observations) increase in exposure (normalized and corrected for measurement error). Only exposures with an uncorrected sex interaction or sex-specific P-value < 5% are reported. The dot displays the coefficient estimate, and the vertical line its 95% CI. Associations were adjusted for gestational duration (simple and quadratic terms), sex of the newborn, parity, maternal height, maternal weight before pregnancy (using a broken stick model with a knot at 60 kg), maternal smoking during the second trimester of pregnancy, maternal education, season of conception and cohort (fixed effect variable). DDT, dichlorodiphenyltrichloroethane; PFOS, perfluorooctane sulfonate; T3, averaged over the third trimester of pregnancy.