Table 1.
Summary of the features of two women with COVID-19
| Clinical characteristics | Patient 1 | Patient 2 | SARS-CoV-2 RNA testing | Patient 1 | Patient 2 | ||
|---|---|---|---|---|---|---|---|
| Age (years) | 38 | 42 | Sample type | Sample date | Result (cycle threshold per target) | Sample date | Result (cycle threshold per target) |
| Gestational age on admission | 34 weeks, 4 days | 37 weeks, 3 days | Breast milk 1 | March 31, 2020 | Positive (E: 34.3; RdRP: 37.1; N: 36.7) | March 29, 2020 | Negative |
| Onset to delivery (days) | 8 | 8 | Breast milk 2 | April 1, 2020 | Positive (E: 33.8, RdRP: 34.3; N: 37.3) | March 30, 2020 | Negative |
| Complications | Foetal distress | None | Breast milk 3 | April 2, 2020 | Negative | March 31, 2020 | Negative |
| Signs and symptoms | Breast milk 4 | April 3, 2020 | Positive (E: 37.3; RdRP: 36.1; N: 38.3) | April 1, 2020 | Negative | ||
| Fever | Yes | No | Breast milk 5 | April 4, 2020 | Negative | April 2, 2020 | Negative |
| Myalgia/Arthralgia | No | No | Breast milk 6 | April 6, 2020 | Negative | April 5, 2020 | Negative |
| Cough | No | Yes | Amniotic fluid | March 28, 2020 | Negative | March 26, 2020 | Negative |
| Dyspnoea | Yes | No | Cord blood | March 28, 2020 | Positive (E: 28.3; RdRP: 29.9; N: 28.9) | March 26, 2020 | Negative |
| Sore throat | No | No | Placental tissue | March 28, 2020 | Positive (E: 22.6; RdRP: 23.5; N: 23.5) | March 26, 2020 | Negative |
| Chest pain | No | No | Neonatal throat swab 1 | March 28, 2020 | Negative | March 26, 2020 | Negative |
| Diarrhoea | Yes | No | Neonatal throat swab 2 | March 31, 2020 | Negative | March 28, 2020 | Negative |
| Laboratory characteristics | Patient 1 | Patient 2 |
| White blood cell count (×109 cells/L) | 5.37 | 12.92 |
| Lymphocyte count (×109 cells/L) | 0.64 | 0.80 |
| Platelet count (×109 cells/L) | 106 | 405 |
| C-reactive protein concentration (mg/L) |
91.3 |
125.7 |
| Treatments after delivery |
Patient 1 |
Patient 2 |
| Supplemental oxygen | Yes | No |
| Lopinavir/ritonavir | Yes | Yes |
| Azithromycin | Yes | Yes |
| Hydroxychloroquine | Yes | Yes |
E, envelope protein gene; RdRP, RNA-dependent RNA polymerase gene; N, nucleocapsid protein gene.