Skip to main content
. 2020 Jun 2;9:e56991. doi: 10.7554/eLife.56991

Table 6. Top 45 differentially regulated genes in dithranol-treated psoriatic skin of c-Jun/JunB knockout mice compared to that of vehicle-treated controls (p<0.05, fold change (FC) >1.5).

Probe set ID Gene symbol Gene title Fold change
TC0Y00000006.mm.2 Eif2s3y Eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked 10,37
TC0Y00000233.mm.2 Uty Ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome 6,38
TC0Y00000235.mm.2 Ddx3y DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked 5,40
TC0900000047.mm.2 Mmp3 Matrix metallopeptidase 3 3,64
TC0Y00000079.mm.2 Ssty2 Spermiogenesis specific transcript on the Y 2 3,31
TC0100001632.mm.2 Ifi209 Interferon activated gene 209 3,23
TC0500002755.mm.2 Cxcl9 Chemokine (C-X-C motif) ligand 9 2,85
TC0300003133.mm.2 Ifi44 Interferon-induced protein 44 2,69
TC0100003591.mm.2 Ifi213 Interferon activated gene 213 2,53
TC0100001634.mm.2 Ifi208 Interferon activated gene 208 2,49
TC1900000217.mm.2 Ms4a4c Membrane-spanning 4-domains, subfamily A, member 4C 2,45
TC0300002684.mm.2 Chil3 Chitinase-like 3 2,39
TC0100003550.mm.2 Slamf7 SLAM family member 7 2,33
TC0500000922.mm.2 Cxcl13 Chemokine (C-X-C motif) ligand 13 2,26
TC1900000500.mm.2 Ifit2 Interferon-induced protein with tetratricopeptide repeats 2 2,20
TC0500002840.mm.2 Plac8 Placenta-specific 8 2,20
TC0700001630.mm.2 Adm Adrenomedullin 2,15
TC1900000501.mm.2 Ifit3 Interferon-induced protein with tetratricopeptide repeats 3 2,13
TC1800000610.mm.2 Iigp1 Interferon inducible GTPase 1 2,07
TC0300001446.mm.2 Gbp3 Guanylate binding protein 3 2,07
TC0300003134.mm.2 Ifi44l Interferon-induced protein 44 like 2,05
TC1900000502.mm.2 Ifit3b Interferon-induced protein with tetratricopeptide repeats 3B 2,02
TC0400003296.mm.2 Skint5 Selection and upkeep of intraepithelial T cells 5 −2,37
TC0300000482.mm.2 Aadac Arylacetamide deacetylase −2,37
TC1100000469.mm.2 Fndc9 Fibronectin type III domain containing 9 −2,39
TC0300002399.mm.2 Lce6a Late cornified envelope 6A −2,42
TC0300002409.mm.2 Lce1i Late cornified envelope 1I −2,44
TC0300002412.mm.2 Kprp Keratinocyte expressed, proline-rich −2,44
TC0300000846.mm.2 Hrnr Hornerin −2,48
TC0300002407.mm.2 Lce1g Late cornified envelope 1G −2,49
TC1600000324.mm.2 Fetub Fetuin beta −2,53
TC1300001377.mm.2 Akr1c18 Aldo-keto reductase family 1, member C18 −2,56
TC0300002406.mm.2 Lce1f Late cornified envelope 1F −2,57
TC1500001714.mm.2 Slurp1 Secreted Ly6/Plaur domain containing 1 −2,57
TC1500002344.mm.2 Gsdmc2 Gasdermin C2 −2,59
TC1000000145.mm.2 Il20ra Interleukin 20 receptor, alpha −2,66
TC0700000443.mm.2 Cyp2b19 Cytochrome P450, family 2, subfamily b, polypeptide 19 −2,70
TC0100000103.mm.2 Ly96 Lymphocyte antigen 96 −2,89
TC0700000778.mm.2 Klk5 Kallikrein related-peptidase 5 −3,15
TC0300003252.mm.2 Clca3a2 Chloride channel accessory 3A2 −3,20
TC0900002312.mm.2 Elmod1 ELMO/CED-12 domain containing 1 −3,20
TC0300002401.mm.2 Lce1a1 Late cornified envelope 1A1 −3,26
TC0700000484.mm.2 Fcgbp Fc fragment of IgG binding protein −3,83
TC0300002405.mm.2 Lce1e Late cornified envelope 1E −4,16
TC1500002274.mm.2 Krt2 Keratin 2 −5,95