Figure 4.

Metabolic activity of MG-63 cells by reduction of AlamarBlue on Days 1, 3 and 6 for extracts diluted in EMEM by the factors 1:1 (undiluted) and 1:4 from reference TiO₂ scaffolds (Sc, brown columns), TiO₂ scaffolds containing Aln-loaded MPs attached with collagen (Sc Aln, blue columns). Additionally, results of MG-63 cells cultured in Aln solutions in EMEM are shown (100, 50, 10, 5 and 1 µg/ml Aln, violet columns). as control, activity of cells cultured in EMEM is shown (red columns). Mean ± S.D. ***P < 0.001.