Table 1.

BRCA1/2 testing criteria in patients with breast cancer.

Criterion	Reason for Testing		Category
1	Family history of known deleterious BRCA1/2 gene mutation		Family History
2	Diagnosed with breast cancer ≤ 45 years old		Young Age
3	Diagnosed with breast cancer ≤ 50 years old and an additional breast cancer primary		High Risk Cancer
4	Diagnosed with breast cancer	Family History of one of the following:	Family History
	≤50 years old and…	≥1 close relative with pancreatic cancer
		≥1 close relative with prostate cancer An unknown or limited family history
5	Diagnosed with breast cancer ≤ 60 years old with TNBC		High Risk Cancer
6	Diagnosed with breast cancer at any age and…	Family History of one of the following:	Family History
		≥1 close relative with breast cancer diagnosed at age ≤50
		≥1 close relative with ovarian carcinoma
		≥1 close relative with male breast cancer
		Ethnicity with higher mutation frequency (e.g., Ashkenazi Jewish)
7	Personal history of male breast cancer		High Risk Cancer