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. 2020 Apr 24;111(6):1190–1202. doi: 10.1093/ajcn/nqaa076

TABLE 3.

Median [IQR] percentage relative abundances of sequencing counts representing fecal bacterial genera at 3, 6, 9, and 12 mo of age from either BF, MF, NLB, or SF infants1

Age Genus BF NLB MF SF FDR
3 Bifidobacterium 13.791 [10–33]a 24.195 [14–35]a 7.919 [2–12]b 0.021
3 f__Clostridiaceae 0.026 [0–0]a 0.279 [0–1]b 0.672 [0–3]b 0.002
3 f__Peptostreptococcaceae 0.053 [0–0]a 0.219 [0–1]a 2.225 [1–4]b <0.001
3 f__Ruminococcaceae 0.087 [0–1]a 0.448 [0–1]b 2.081 [1–4]c <0.001
3 SMB53 0.015 [0–0]a 0.057 [0–0]a 0.373 [0–1]b <0.001
6 Bifidobacterium 23.625 [15–39]a 27.52 [12–34]a 3.361 [0–7]b <0.001
6 Coprococcus 0.021 [0–0]a 0.293 [0–1]b 0.481 [0–2]b <0.001
6 Enterococcus 0.044 [0–0]a 0.04 [0–0]a 0 [0–0]b 0.017
6 f__Clostridiaceae 0.024 [0–0]a 0.158 [0–1]ab 0.571 [0–5]b 0.007
6 f__Lachnospiraceae 0.115 [0–1]a 0.901 [0–2]b 4.17 [2–7]c <0.001
6 o__Clostridiales 0 [0–0]a 0 [0–0]a 0.226 [0–0]b <0.001
6 Roseburia 0 [0–0]a 0 [0–0]a 0.088 [0–2]b 0.013
6 SMB53 0.007 [0–0]a 0.071 [0–0]a 0.616 [0–1]b <0.001
9 Akkermansia 0 [0–0]a 0.017 [0–0]b 0.107 [0–2]b 0.038
9 Bifidobacterium 17.951 [11–37]a 11.847 [10–30]a 6.065 [3–17]b 0.038
9 Clostridium 1.096 [0–4]a 0.047 [0–0]b 0.032 [0–0]b 0.026
9 f__Peptostreptococcaceae 0.064 [0–1]a 0.282 [0–1]a 2.447 [1–7]b 0.005
9 f__Veillonellaceae 0.027 [0–2]a 7.207 [1–18]b 0 [0–0]a 0.01
9 o__Clostridiales 0 [0–0]a 0 [0–0]a 0.228 [0–0]b <0.001
9 SMB53 0 [0–0]a 0.076 [0–0]a 1.227 [1–2]b <0.001
12 Bifidobacterium 14.202 [13–19]a 8.631 [4–12]ab 15.18 [6–22]a 4.604 [2–6]b 0.008
12 f__Lachnospiraceae 1.267 [1–2]a 1.473 [1–3]ab 2.894 [2–5]bc 3.836 [2–6]c 0.012
12 Veillonella 0.836 [0–4]a 0.415 [0–1]ab 0.36 [0–1]ab 0.25 [0–0]b 0.047
1

Featured genera were found to be significantly altered by diet by both Kruskal–Wallis and DESeq2 Wald assessments. Zeros indicate abundances of genera lower than the quartiles. See Supplemental Tables 4 and 5 for full assessments of each statistical output. Only the FDRs for the Kruskal–Wallis tests are provided. Groups with different letters differ according to Dunn's test. Sample sizes range from 10 to 20 per diet group at 3, 6, 9, and 12 mo of age. BF, breastfed; FDR, false discovery rate; MF, cow milk–based formula; NLB, no longer breastfeeding; SF, soy-based formula.