TABLE 7.
Fecal SCFAs from a subset of study population following random allocation to almond and control snacks1
| Control, n = 17 | Almonds, n = 18 | Main comparison between groups3 | |||
|---|---|---|---|---|---|
| SCFA, μmol/g | Baseline2 | Change | Baseline2 | Change | |
| Acetic acid | 50.1 (32.3) | −0.56 (−8.78, 9.90) | 49.4 (31.8) | 4.61 (−4.47, 13.68) | 4.05 (−9.05, 17.15) |
| Propionic acid | 12.8 (7.3) | 2.26 (−2.14, 6.66) | 13.8 (10.5) | −0.68 (−4.96, 3.59) | −2.94 (−9.13, 3.24) |
| Isobutyric acid | 1.91(0.5) | 0.04 (−0.41, 0.50) | 1.6 (1.1) | 0.27 (−0.18, 0.71) | 0.22 (−0.42, 0.87) |
| Butyric acid | 13.6 (8.7) | 0.31 (−3.97, 4.59) | 13.7 (12.9) | 3.06 (−1.10, 7.21) | 2.74 (−3.28, 8.77) |
| Isovaleric acid | 2.2 (0.4) | 0.10 (−0.43, 0.63) | 1.9 (1.4) | 0.30 (−0.22, 0.81) | 0.20 (−0.55, 0.95) |
| Valeric acid | 1.7 (1.2) | 0.11 (−0.22, 0.45) | 2.0 (0.8) | 0.06 (−0.27, 0.38) | −0.06 (−0.52, 0.41) |
| Total SCFA | 90.1 (52.0) | 3.31 (−13.37, 20.0) | 85.4 (68.0) | 7.66 (−8.55, 23.87) | 4.35 (−19.05, 27.75) |
1Values of change and main comparisons of changes between groups are presented as mean (95% CI) generated from estimated marginal means from ANCOVA.
2
Median (IQR) because data are nonnormally distributed. Baseline biomarker values were not different between the 2 groups.
3
ANCOVA, adjusted for baseline outcome value and baseline BMI (mean difference in change from baseline, almonds minus control). ANCOVA assumptions were met. SCFA, short chain fatty acid.