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. Author manuscript; available in PMC: 2020 Jun 3.
Published in final edited form as: Dev Dyn. 2020 Mar 10;249(6):741–753. doi: 10.1002/dvdy.164

Figure 6: E-cadherin staining of distal colon.

Figure 6:

E-cadherin staining by immunohistochemistry on E11.5. Fgfr2IIIb−/− mutant and wild type distal colon. Within the wild type condition, there is a discreet staining of this epithelial cell marker at the cell borders and the epithelium retains a pseudostratified columnar organization (A-C). The Fgfr2IIIb−/− mutant the distal colon display a lack of pseudostratified columnar architecture often co-occurring with a loss of lumen (D-F), at times a diffuse pattern of E-cadherin staining (D,F), rare E-cadherin positive staining cells in the mesenchyme (indicated by the arrow in E), and near the termination of the atresia greatly diminished E-cadherin staining (F). Scale bar is 50 μm.