Table 2: Statistical analysis of cellular proliferation across age groups and colonic regions.

Examination of cellular proliferation rates as determined by PHH3 staining in E10.5 and E11.5 wild type and Fgfr2IIIb−/− mutant intestines across 50 μm colon segments. Epithelial cells within that region were pooled together as a set to examine differences between distal and proximal colon.

Counts were obtained from stained 5μm sections of intestine.

None of the comparisons yielded statistically significant results despite a trend of decreased cellular proliferation at the distal colon when compared to the proximal region in almost all cases.

Age	Wild type proximal colon mean proliferation rate	Wild type distal colon mean proliferation rate	P-value
E10.5	3.89%	2.75%	not significant
E11.5	2.60%	2.31%	not significant
Age	Fgfr2IIIb −/− mutant proximal colon mean proliferation rate	Fgfr2IIIb −/− mutant distal colon mean proliferation rate	P-value
E10.5	3.33%	0.98%	not significant
E11.5	2.62%	1.27%	not significant
Age	Wild type proximal colon mean proliferation rate	Fgfr2IIIb −/− mutant proximal colon mean proliferation rate	P-value
E10.5	3.89%	3.33%	not significant
E11.5	2.60%	2.62%	not significant
Age	Wild type distal colon mean proliferation rate	Fgfr2IIIb −/− mutant distal colon mean proliferation rate	P-value
E10.5	2.75%	0.98%	not significant
E11.5	2.31%	1.27%	not significant