Table 4.

Univariate and multivariate analyses of overall survival using a Cox proportional hazards model in patients with cervical adenocarcinoma

Factors	Patients	Univariate analysis			Mutivariate analysis
	n	HR	95% CI	p value	HR	95% CI	p value
Age (y)
< 60	58	0.58	0.233–1.446	0.243
≥ 60	24	Ref
FIGO stage
< IIB	58	0.222	0.087–0.565	0.002	0.968	0.284–3030	0.958
≥ IIB	24	Ref			Ref
Histology
Non-gastric type	69	0.67	0.222–2.021	0.477
Gastric type	13	Ref
Tumor size (mm)
< 40	50	0.168	0.060–0.468	0.001	0.171	0.036–0.812	0.026
≥ 40	32	Ref			Ref
Metastasis pelvic lymphnode
Negative	65	0.515	0.202–1.309	0.163
Positive	17	Ref
Metastasis paraaortic lymphnode
Negative	79	0.321	0.074–1.405	0.131
Positive	3	Ref
Metastasis distance
Negative	81	0.026	0.002–0.283	0.003	0.102	0.009–1.205	0.07
Positive	1	Ref			Ref
Metastasis LVI
Negative	29	0.053	0.007–0.416	0.005	0.034	0.002–0.521	0.015
Positive	39	Ref			Ref
PD-1
Negative	59	Ref			Ref
Positive	23	6.765	0.903–50.705	0.063	5.311	0.549–51.377	0.149
PD-L1
Negative	66	Ref			Ref
Positive	16	1.331	0.382–2.196	0.667	2.414	0.439–13.264	0.311
CD8
Negative	27	Ref			0.286	0.055–1.498	0.139
Positive	55	1.694	0.609–4.710	0.313	Ref