Table 3.

Means ± SD at baseline, at end of week 2 and week 12 for the two study groups (Group 1, patients receiving Tiszasüly hot mud pack; and group 2, patients receiving Kolop hot mud pack) and between-group differences at end of week 2 and week 12 show the effects of Tiszasüly and Kolop mud packs on pain, function, and quality of life in patients with knee osteoarthritis

Measured clinical variables	Treatment groups	Baseline visit		Week 2 visit		Week 12 visit		p 1–2 (significance level, difference between visits)	p 1–3 (significance level, difference between visits)	p 2–3 (significance level, difference between visits)
		Mean ± SD	p (significance level, between group difference)	Mean ± SD	p (significance level, between group difference)	Mean ± SD	p (significance level, between group difference)
WOMAC sum.	Tiszasüly (n = 29)	888.62 ± 354.47	0.188	651.10 ± 382.90	0.126	608.17 ± 445.19	0.201	0.002	0.001	0.399
	Kolop (n = 31)	1048.74 ± 405.61		808.77 ± 389.09		773.35 ± 491.16		< 0.001	< 0.001	0.445
Koos score	Tiszasüly (n = 29)	52.15 ± 9.46	0.083	50.98 ± 21.68	0.790	50.57 ± 21.63	0.717	0.991	0.905	0.762
	Kolop (n = 31)	57.40 ± 12.81		51.68 ± 17.34		49.81 ± 19.69		0.046	0.039	0.943
EQ5D score	Tiszasüly (n = 29)	0.613 ± 0.177	0.488	0.694 ± 0.249	0.893	0.704 ± 0.265	0.327	0.039	0.028	0.689
	Kolop (n = 31)	0.490 ± 0.307		0.734 ± 0.146		0.652 ± 0.255		< 0.001	< 0.001	0.193
EQ5D VAS score	Tiszasüly (n = 29)	0.601 ± 0.145	0.577	0.680 ± 0.199	0.911	0.700 ± 0.213	0.313	0.024	0.011	0.647
	Kolop (n = 31)	0.534 ± 0.192		0.708 ± 0.150		0.655 ± 0.187		< 0.001	< 0.001	0.214
VAS score of knee pain	Tiszasüly (n = 29)	57.83 ± 14.16	0.329	24.10 ± 21.93	0.009	29.52 ± 26.15	0.296	< 0.001	< 0.001	0.160
	Kolop (n = 31)	61.39 ± 14.56		36.61 ± 17.50		35.16 ± 25.02		< 0.001	< 0.001	0.509
Lequesne sum index	Tiszasüly (n = 29)	10.45 ± 2.65	0.784	8.21 ± 3.93	0.953	7.72 ± 4.17	0.267	0.001	0.001	0.354
	Kolop (n = 31)	10.95 ± 3.70		8.00 ± 3.68		9.24 ± 4.49		< 0.001	0.004	0.046