Table 2.
Top 10 DE Proteins in ICM vs Donor left ventricular myocardium.
| Protein | Log2 FC | FC | t | P value | Adjusted P value |
|---|---|---|---|---|---|
| SAA1 | −3.32 | −10 | −8.52 | 1.08 × 10−10 | 2.84 × 10−07 |
| TF | 1.16 | 2.23 | 7.37 | 3.84 × 10−09 | 4.53 × 10−06 |
| VWF | 1.47 | 2.77 | 7.28 | 5.20 × 10−09 | 4.53 × 10−06 |
| FBLN5 | 1.45 | 2.74 | 6.91 | 1.77 × 10−08 | 1.16 × 10−05 |
| EFEMP1 | 1.78 | 3.43 | 6.26 | 2.06 × 10−07 | 1.08 × 10−04 |
| SERPINA4 | 1.35 | 2.55 | 6.12 | 3.59 × 10−07 | 1.56 × 10−04 |
| MFAP4 | 1.65 | 3.14 | 5.99 | 4.47 × 10−07 | 1.67 × 10−04 |
| COL6A2 | 1.14 | 2.20 | 5.80 | 7.21 × 10−07 | 2.36 × 10−04 |
| CYLC1 | 1.01 | 2.01 | 5.75 | 8.43 × 10−07 | 2.45 × 10−04 |
| SERPIND1 | 1.19 | 2.28 | 5.60 | 1.41 × 10−06 | 3.57 × 10−04 |
Estimates were derived using the linear regression model adjusted for gender, where nICM = 15 and ndonor = 15; p values were adjusted for multiple comparisons by the Benjamini–Hochberg method. (See Supplementary Data 1).
FC fold change, t t-statistic.