Fig. 2. Lower mitochondrial complex I function in Ndufs4^GT/GT mice did not negatively impact locomotor function or grip strength, but Ndufs4^GT/GT mice showed slightly more anxiety-related behavior following stress.

a Average latency to fall from a rotating rod accelerating from 4 to 40 rpm in 300s. b Average latency to fall from the rod during the three individual trials investigating the ability of the mice to adapt to the test. c The average grip strength of the animals was measured using only their forepaws or (d) all four paws. The grip strength test measured the peak force (in gram force, gf) of each animal. e Representative locomotion tracks from the open field with the center area delineated. Animals freely explored the open field for 10 min. Traces of all animals during the open field are shown in Fig. S8. f The total distance moved in meters, (g) average time spent in the center, and (h) defecation during the 10min in the open field were measured. Graphs show average ±SEM, with each black dot representing the result of an individual animal. *p < 0.05, **p < 0.01, and ***p < 0.001, and ^#p < 0.07.