Table 3.
Diltiazem (n = 34) |
Control (n = 83) |
Difference (95% CI) |
p | |
---|---|---|---|---|
Cardiovascular system | ||||
Hypotension* | 14 (41.2) | 31 (37.4) | 3.8% (−15.3 to 24.1) | 0.699 |
Bradycardia** | 5 (14.7) | 3 (3.6) | 11.1% (−27.5 to 0.0) | 0.031 |
Need for catecholamines | 19 (55.9) | 32 (38.6) | 17.3% (−3.5 to 36.9) | 0.086 |
Norepinephrin (µg/kg/min) | 0.09 (±0.13) | 0.04 (±0.07) | 0.05 (0.00 to 0.10) | 0.041 |
Dobutamin (µg/kg/min) | 0.76 (±1.39) | 0.76 (±1.88) | −0.05 (−0.68 to 0.59) | 0.888 |
Atrial fibrillation (new onset) | 3 (8.8) | 9 (10.8) | −2.0% (−13.1 to 13.8) | 0.744 |
Atrial fibrillation (new onset) as a solitary complication | 1 (2.9) | 3 (3.6) | −0.7% (−8.2 to 12.2) | 0.856 |
Respiratory system | ||||
Duration of respiratory support in the ICU (h)*** | 24.9 (±80.4) | 26.2 (±100.0) | −1.3 (−37.2 to 34.5) | 0.946 |
Pneumonia | 3 (8.8) | 11 (13.2) | −4.4% (−16.0 to 11.5) | 0.503 |
Other | ||||
CVVH | 1 (2.9) | 2 (2.4) | 0.5% (−6.3 to 13.5) | 0.869 |
Sepsis | 2 (5.9) | 9 (10.8) | −4.9% (−15.3 to 9.7) | 0.404 |
Anastomotic leakage | 3 (8.8) | 12 (14.4) | −5.6% (−17.4 to 10.3) | 0.408 |
Mortality | ||||
30 days | 3 (8.8) | 4 (4.8) | 4.0% (−5.5 to 19.4) | 0.407 |
90 days | 3 (8.8) | 5 (6.0) | 2.8% (−7.1 to 18.5) | 0.586 |
Data are the mean ± standard deviation or number (%)
CI confidence interval, ICU intensive care unit, CVVH continuous veno-venous hemofiltration
*Systolic pressure <90 mmHg, **heart rate <50 beats/min, ***ventilation and noninvasive ventilation