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. 2020 May 27;11:1097. doi: 10.3389/fmicb.2020.01097

FIGURE 2.

FIGURE 2

Fut8+/– mice is susceptive to S. Typhi infection. (A) Fut8+/– and Fut8+/– mice were infected with S. Typhi every day by oral gavage for 7 days at a concentration of 1 × 108 CFU/ml. (B) Following oral infection with S. Typhi, mice were weighed daily and the percent change in weight from days 1 to 8 is shown. Data were analyzed with a one-way ANOVA using Bonferroni correction (Fut8+/+, n = 3; Fut8+/+ + S. Typhi, n = 3; Fut8+/–, n = 3; Fut8+/– + S. Typhi, n = 3; **p < 0.01; ***p < 0.001). (C) Sections from the mouse intestines were stained with H&E. The infection of the S. Typhi-infected Fut8+/– mice was found more severe compared to the S. Typhi-infected Fut8+/+ mice. And the infection was expressed in the disruption and swelling of intestinal villus, cell infiltration and thickening of muscular layer.