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Interplay of metabolic, neuro-endocrine and immune system in the obese state in the context of vaccination. Interactions between metabolic, neuro-endocrine and immune system in the obese state that influence vaccine responses in a sex-dependent manner. Abbreviations: WAT, white adipose tissue; LepR, leptin receptor; ERα/β, estrogen receptor α/β; CNS, central nervous system; Abs, antibodies; Th2, T helper cells type 2.
