Table 2.

Correlation of TBE NT titer kinetics with BMI, metabolic parameters, and hormones.

	log NT at d0		NT increase d0_28		NT increase d7_28		NT decrease d28_180
	rs	p	rs	p	rs	p	rs	p
(A) Correlation of log TBE NT titers at d0, log TBE NT titer increase d0_d28, log TBE NT titer increase d7_d28, and log TBE NT titer decline d28_d180 with body mass index (BMI) and metabolic parameters (insulin, leptin, triglycerides, cholesterol ratio, HDL cholesterol) measured before vaccination (d0).
BMI	−0.20	0.085	$0.28$	0.017*	$0.28$	0.014*	$-0.27$	0.019*
Insulin	$-0.24$	0.038*	$0.29$	0.011*	$0.29$	0.012*	$-0.26$	0.024*
Leptin	−0.09	0.470	$0.27$	0.022*	$0.24$	0.041*	−0.18	0.115
TG	−0.23	0.052	0.20	0.086	0.11	0.341	$-0.24$	0.035*
Chol R	−0.23	0.050	0.09	0.408	0.05	0.638	−0.20	0.079
HDL	0.20	0.082	−0.10	0.391	0.00	0.997	0.23	0.050
(B, C) Correlation of log TBE NT titers at d0, log TBE NT titer increase d0_d28, log TBE NT titer increase d7_d28, and log TBE NT titer decline d28_d180 with levels of testosterone, estrogen, progesterone, FSH, and LH measured before vaccination (d0) in (B) men and (C) women.
(B) MALES
Testosterone	$0.388$	0.025*	−0.323	0.067	−0.203		0.339	0.053
Estrogen	−0.028		−0.066		−0.031		0.115
Progesterone	−0.094		−0.025		0.194		−0.071
FSH	0.057		−0.074		−0.016		0.114
LH	0.091		$-0.391$	0.024*	−0.199		$0.380$	0.029*
(C) FEMALES
Testosterone	−0.257		0.143		−0.125		−0.147
Estrogen	0.124		−0.194		−0.125		−0.021
Progesterone	−0.255		0.117		$-0.315$	0.048*	−0.093
FSH	−0.036		0.266		0.286	0.073	−0.026
LH	−0.116		0.242		$0.337$	0.033*	−0.055

Shown is Spearman correlation coefficient r_s (+ or −) and the respective p-value;

^*p ≤ 0.05, r_s indicated in red.