TABLE 6.
Featuresof the studies included in the selective review of reviews.
| Cluster | Keyword | Title | Study | Topic | Discipline | Validity compared to on-road testing | Validity compared to laboratory testing | Fidelity | Systematic review |
| 1 | Attention | Driving and neurologic disorders | Drazkowski and Sirven, 2011 | Neurologic Disorders | Neurology | nd | nd | nd | 1 |
| 1 | Attention | Parkinson disease and driving: An evidence-based review | Crizzle et al., 2012 | Major Neurocognitive disorders | Health Science | nd | Yes | nd | 1 |
| 1 | Attention | Neural correlates of simulated driving while performing a secondary task: A review | Palmiero et al., 2019 | Distraction fMRI | Health Science | nd | nd | nd | 1 |
| 1 | Dementia | Driving and dementia: A review of the literature | Lloyd et al., 2001 | Major Neurocognitive disorders | Occupational Therapy | No | nd | nd | 1 |
| 1 | Dementia | Driving and dementia: A review of the literature | Brown and Ott, 2004 | Major Neurocognitive disorders | Psychiatry | Yes | Yes | nd | 1 |
| 1 | Dementia | Systematic review of driving risk and the efficacy of compensatory strategies in persons with dementia | Man-Son-Hing et al., 2007 | Major Neurocognitive disorders | Geriatry | Yes | nd | nd | 1 |
| 1 | Dementia | Brain morphometry and functional imaging techniques in dementia: methods, findings and relevance in forensic neurology | Klöppel, 2009 | Major Neurocognitive disorders | Psychiatry | nd | Yes | nd | 1 |
| 1 | Dementia | Car drivers with dementia: different complications due to different etiologies? | Piersma et al., 2016 | Major Neurocognitive disorders | Psychology | Yes | Yes | nd | 1 |
| 1 | Driving simulation | Validation of driving simulators | Davison et al., 2011 | Vision | Ophthalmology | nd | nd | nd | 1 |
| 1 | Driving simulation | Saccadic velocity as an arousal index in naturalistic tasks | Di Stasi et al., 2013a | Workload/Fatigue | Psychology | nd | nd | nd | 1 |
| 1 | Driving simulation | Inside the clinical evaluation of sleepiness: Subjective and objective tools | Baiardi and Mondini, 2019 | Sleepiness | Medicine | Yes | Yes | nd | 1 |
| 1 | Driving simulation | Driving status of patients with generalized spike–wave on EEG but no clinical seizures | Antwi et al., 2019 | Epilepsy and Driving | Neurology | nd | nd | nd | 1 |
| 1 | Sleepiness | Neuropsychological function in obstructive sleep apnea | Engleman and Joffe, 1999 | Sleepiness | Medicine | Yes | Yes | nd | 1 |
| 1 | Sleepiness | Daytime sleepiness and its evaluation | Cluydts et al., 2002 | Sleepiness | Psychology | No | nd | nd | 1 |
| 1 | Sleepiness | Cognition and daytime functioning in sleep-related breathing disorders | Jackson et al., 2011 | Sleepiness | Health Science | nd | nd | nd | 1 |
| 1 | Sleepiness | Diagnostic approach to sleep-disordered breathing | Thurnheer, 2011 | Sleepiness | Pneumology | nd | nd | nd | 1 |
| 1 | Sleepiness | Hypersomnolence and traffic safety | Gupta et al., 2017 | Sleepiness | Psychiatry | nd | nd | nd | 1 |
| 1 | Sleepiness | Subjective and objective assessment of hypersomnia | Murray, 2017 | Sleepiness | Neurology | nd | Yes | nd | 1 |
| 1 | Sleepiness | Determinants of policy decisions for non-commercial drivers with OSA: An integrative review | Rizzo et al., 2018 | Sleepiness | Medicine | nd | nd | nd | 1 |
| 1 | Sleepiness | Driving simulators in the clinical assessment of fitness to drive in sleepy individuals: A systematic review | Schreier et al., 2018 | Sleepiness | Neurology | Mixed results | nd | nd | 2 |
| 1 | Sleepiness | Narrative review: Do spontaneous eye blink parameters provide a useful assessment of state drowsiness? | Cori et al., 2019 | Sleepiness | Medicine | Yes | Yes | nd | 1 |
| 2 | Alcohol | Using virtual reality to study alcohol intoxication effects on the neural correlates of simulated driving | Calhoun et al., 2005 | Alcohol consumption | Psychiatry | Yes | nd | nd | 1 |
| 2 | Alcohol | A selective review of simulated driving studies: Combining naturalistic and hybrid paradigms, analysis approaches, and future directions | Calhoun and Pearlson, 2012 | Neuroimaging and Alcohol | Psychology | Yes | nd | Yes | 1 |
| 2 | Alcohol | The sensitivity of laboratory tests assessing driving related skills todose-related impairment of alcohol: A literature review | Jongen et al., 2016 | Alcohol | Pharmacology | No | nd | nd | 2 |
| 2 | Alcohol | A systematic review of the evidence for acute tolerance to alcohol – the “Mellanby effect” | Holland and Ferner, 2017 | Alcohol | Medicine | nd | Yes | nd | 2 |
| 2 | Alohol | Effects of acute alcohol consumption on measures of simulated driving: A systematic review and meta-analysis | Irwin et al., 2017 | Alcohol consumption | Health Science | Yes | nd | nd | 3 |
| 2 | Driving | Cognitive dysfunction in sleep disorders | Fulda and Schulz, 2001 | Sleepiness | Psychology | Mixed results | Mixed results | nd | 1 |
| 2 | Driving | Outcome measurement in sleep medicine practice and research. Part 2: assessment of neurobehavioral performance and mood | Weaver, 2001 | Sleepiness | Nursing | nd | Yes | nd | 1 |
| 2 | Driving | Are opioid-dependent/tolerant patients impaired in driving-related skills? A structured evidence-based review | Fishbain et al., 2003 | Medication assumption | Psychiatry | nd | nd | nd | 1 |
| 2 | Driving | Driving simulators in clinical practice | George, 2003 | Sleepiness | Medicine | No | nd | Yes | 1 |
| 2 | Driving | Residual effects of sleep medication on driving ability | Verster et al., 2004 | Medication assumption | Pharmacology | No | nd | nd | 1 |
| 2 | Driving | The assessment of driving abilities | Marcotte and Scott, 2004 | Assessment of driving skills | Psychiatry | Yes | Mixed results | No | 1 |
| 2 | Driving | Conversation effects on neural mechanisms underlying reaction time to visual events while viewing a driving scene: fMRI analysis and asynchrony model | Hsieh et al., 2009 | Distraction fMRI | Communication science | nd | nd | nd | 1 |
| 2 | Driving | Functional consequences of HIV-associated neuropsychological impairment | Gorman et al., 2009 | Major Neurocognitive disorders(hiv) | Psychiatry | Yes | Yes | Mixed results | 1 |
| 2 | Driving | Driving ability in Parkinson’s disease: Current status of research | Klimkeit et al., 2009 | Major Neurocognitive Disorders | Psychology | Yes | Yes | nd | 1 |
| 2 | Driving | Phoning while driving II: A review of driving conditions influence | Collet et al., 2010 | Distraction | Psychology | Mixed results | nd | Mixed results | 1 |
| 2 | Driving | A review of driving simulator parameters relevant to the operation enduring freedom/operation Iraqi freedom veteran population | Kraft et al., 2010 | Iraqi Veterans/DS’s parameters operation | Medicine | Yes | Yes | yes | 1 |
| 2 | Driving | Zopiclone as positive control in studies examining the residual effects of hypnotic drugs on driving ability | Verster et al., 2011 | Medication assumption | Pharmacology | Yes | Yes | nd | 3 |
| 2 | Driving | Systematic review of the quality and generalizability of studies on the effects of opioids on driving and cognitive/psychomotor performance | Mailis-Gagnon et al., 2012 | Medication assumption | Medicine | nd | Mixed results | No | 2 |
| 2 | Driving | Does personality predict driving performance in middle and older age? An evidence-based literature review | Nichols et al., 2012 | Personality | Psychology | No | nd | nd | 2 |
| 2 | Driving | Epilepsy and driving: Potential impact of transient impaired consciousness | Chen et al., 2014 | Epilepsy | Neurology | Yes | nd | nd | 1 |
| 2 | Driving | Saccadic peak velocity as an alternative index of operator attention: A short review | Di Stasi et al., 2013b | Saccadic velocity/attention | Psychology | nd | nd | nd | 1 |
| 2 | Driving | The impact of depression on driver performance | Wickens et al., 2014 | Mental health | Health Science | Yes | nd | nd | 1 |
| 2 | Driving | Driving in Parkinson’s disease | Özdilek and Uç, 2014 | Major Neurodegenerative disorders | Neurology | nd | Yes | nd | 1 |
| 2 | Driving | The racer’s brain – How domain expertise is reflected in the neural substrates of driving | Lappi, 2015 | Neural substrates of driving | Psychology | nd | nd | nd | 2 |
| 2 | Driving | Mirtazapine as positive control drug in studies examining the effects of antidepressants on driving ability | Verster et al., 2015 | Medication assumption | Pharmacology | nd | nd | nd | 1 |
| 2 | Driving | High risk driving in treated and untreated youth with attention deficit hyperactivity disorder: Public health implications | Jillani and Kaminer, 2016 | ADHD | Medicine | nd | nd | nd | 2 |
| 2 | Driving | Driving with a neurodegenerative disorder: An overview of the current literature | Jacobs et al., 2017 | Major Neurocognitive Disorders | Neurology | Yes | Yes | yes | 1 |
| 2 | Driving | Covert hepatic encephalopathy: Can my patient drive? | Shaw and Bajaj, 2017 | Hepatic Encephalopathy | Gastroenterology | nd | Yes | nd | 1 |
| 2 | Driving | Smart in-vehicle technologies and older drivers: A scoping review | Classen et al., 2019 | Aging | Occupational Therapy | No | nd | nd | 2 |
| 2 | Driving | Relationships between cognitive functions and driving behavior in Parkinson’s disease | Ranchet et al., 2012 | Cognition and driving in Parkinson | Psychology | Yes | Yes | nd | 1 |
| 3 | Driving simulator | The development of driving simulators: toward a multisensory solution | Pinto et al., 2008 | Development of driving simulator | Psychology | Mixed results | nd | Mixed results | 1 |
| 3 | Driving simulator | Rehabilitation of combat-returnees with traumatic brain injury | Lew et al., 2009 | Rehabilitation | Medicine | Yes | Yes | Yes | 1 |
| 3 | Driving simulator | Validation of driving simulators | Shechtman, 2010 | Validation of driving simulators | Occupational Therapy | Mixed results | nd | Mixed results | 1 |
| 3 | Driving simulator | Nasal continuous positive airway pressure (nCPAP) treatment for obstructive sleep apnea, road traffic accidents and driving simulator performance: A meta-analysis | Antonopoulos et al., 2011 | Effect of nasal continuous positive airway pressure | Medicine | Yes | nd | nd | 3 |
| 3 | Driving simulator | Effects of adaptive cruise control and highly automated driving on workload and situation awareness: A review of the empirical evidence | de Winter et al., 2014 | Automated driving systems | Engineering | nd | nd | nd | 2 |
| 3 | Driving simulator | Establishing an evidence-base framework for driving rehabilitation in Parkinson’s disease: A systematic review of on-road driving studies | Devos et al., 2015 | Major Neurocognitive disorders | Health Science | Yes | Yes | nd | 2 |
| 3 | Driving simulator | The impact of therapeutic opioid agonists on driving-related psychomotor skills assessed by a driving simulator or an onroad driving task: A systematic review | Ferreira et al., 2018 | Medication assumption | Medicine | Yes | Yes | nd | 2 |
| 3 | Driving simulator | Evaluation method regarding the effect of psychotropic drugs on driving performance: A literature review | Iwata et al., 2018 | Drugs consumption | Psychiatry | Mixed results | nd | No | 1 |
| 3 | Driving simulator | Efficacy of training with driving simulators in improving safety in young novice or learner drivers: A systematic review | Martín-delosReyes et al., 2019 | Training for improving driving safety | Medicine | Mixed results | nd | nd | 1 |
| 3 | Driving simulator | Bibliometric analysis of simulated driving research from 1997 to 2016 | Guo et al., 2019 | Bibliometric analysis | Business | nd | nd | nd | 1 |