Table 2.
Baseline clinical characteristics (described in full cohort column) and comparison of clinical characteristics between infants with lower (<50th percentile) and higher (>50th percentile) pre-operative IFABP levels.
| Baseline characteristics | Full cohort | Pre-operative IFABP level ≤50% | Pre-operative IFABP level >50% | p-value ≤50 vs. >50 |
|---|---|---|---|---|
| Pre-operative IFABP level (ng/ml), median (range) | 3.9 (0.2, 51.3) | 1.9 (0.2, 3.9) | 7.8 (4.3, 51.3) | <0.0001 |
| Age at surgery, days; median (range) | 21.5 (1, 120) | 6.0 (1, 119) | 55 (2, 120) | 0.0004 |
| Weight; median (range) | 3.6 (2.1, 7.4) | 3.3 (2.2, 7.4) | 3.8 (2.1, 7.2) | 0.0474 |
| Birthweight; median (range) | 3.1 (1.3, 4.6) | 3.1 (2.3, 4.0) | 3.0 (1.3, 4.6) | 0.1598 |
| Male (%) | 57 (55.3%) | 31 (60.8%) | 25 (50%) | 0.2756 |
| Aristotle Score-Comprehensive; median (range) | 9.0 (3.0, 19.5) | 10 (3.0, 19.5) | 9 (3.0, 15.0) | 0.3177 |
| Aristotle Score-Basic; Median (range) | 9.0 (3.0, 15.0) | 9.0 (3.0, 14.5) | 8.5 (3.0, 15.0) | 0.4033 |
| Pre-operative mechanical ventilation (%) | 32 (31.4%) | 15 (29.4%) | 16 (32%) | 0.7780 |
| Pre-operative inotropic support (%) | 13 (12.6%) | 9 (17.7%) | 4 (8%) | 0.2343 |
| Single ventricle physiology (%) | 29 (28.7%) | 16 (32%) | 12 (24%) | 0.3730 |
| Pre-operative enteral nutrition initiated (%) | 95 (92.2%) | 44 (86.3%) | 50 (100%) | 0.0125 |
| Preterm (%) | 15 (14.7%) | 4 (7.8%) | 11 (22.5%) | 0.0518 |
| Prostaglandins (%) | 51 (50%) | 35 (68.6%) | 15 (30%) | 0.0001 |
Bold values represent statistically significant values (p < 0.05).