Table 4.

Binding energies obtained from docking experiments of astilbin, isoastilbin, neoastilbin, neoisoastilbin, and the respective known enzyme inhibitors galantamine and zileuton over acetylcholinesterase (TcAChE) ( Supplementary Material, Figure S11 ), butyrylcholinesterase (hBuChE) ( Supplementary Material, Figure S12 ) and 5-lipoxygenase (5- hLOX) ( Supplementary Material, Figure S13 ).

Compound	Binding energy (kcal/mol) Acetylcholinesterase (TcAChE)	Binding energy (kcal/mol) Butyrylcholinesterase (hBuChE)	Binding energy (kcal/mol) 5-lipoxygenase (5- hLOX)
Astilbin	−8.92	−9.41	−3.61
Isoastilbin	−8.59	−9.25	−1.17
Neoastilbin	−9.78	−9.38	−1.3
Neoisoastilbin	−10.37	−8.98	2.33
Galantamine	−11.81	−9.5	-
Zileuton	-	-	−7.25