TABLE 1.
Patient | Age |
Co‐morbid Conditions |
Clinical Presentation |
SARS Co‐V‐2 Diagnosis |
Imaging | Treatment | Immunosuppressive Agent Modifications | Outcome |
---|---|---|---|---|---|---|---|---|
1 | 50 |
HIV HTN Asthma, Steatohepatitis Resolved HBV |
Fevers Chills Nasal congestion Cough Anosmia Dysgeusia |
NP swab | None | None | MMF reduced | Recovered |
2 4 | 28 | Lupus‐like syndrome |
Low grade fevers Malaise Sore throat Rhinorrhea |
NP swab | CT chest: normal | Oseltamivir | None | Recovered |
3 7 | 75 |
COPD HTN Heart disease |
Fevers Dyspnea Myalgias |
NP swab |
CT chest: extensive bilateral GGO |
Hydroxychloroquine Lopinavir/ritonavir |
Tacrolimus discontinued MMF discontinued |
Expired |
4 7 | 52 | HTN |
Fevers Dyspnea Diarrhea, Myalgias AKI |
NP swab | CT chest: extensive bilateral GGO |
Hydroxychloroquine Darunavir/cobicistat Colchicine |
Tacrolimus discontinued MMF discontinued |
Remained hospitalized |
5‐40 15 | 32‐77 | Not available |
Fever (58%) Cough (53%) Dyspnea (44%) Myalgias (36%) Diarrhea (22%) |
Not available | Imaging consistent with viral pneumonia (96%) b |
Hydroxychloroquine (86%) Azithromycin (46%) Leronlimab (7%) Tocilizumab (7%) High‐dose glucocorticoids (7%) |
Anti‐metabolite discontinued (86%) Tacrolimus discontinued (21%) |
Mechanic al ventilation (39%) Remained hospitalized (43%) Expired (28%) |
41 8 | 50 |
HTN DM |
Fever Cough |
NP swab | CXR: minimal interstitial lesions | None | None | Recovered |
42 10 | 50 |
Splenectomy ITP PTLD HTN |
Fever Vomiting |
NP swab | CXR diffuse bilateral infiltrates | Lopinavir/ritonavir Hydroxychloroquine Interferon Beta |
Tacrolimus discontinued Everolimus discontinued |
Remained in ICU |
43 11 | 52 | Not available |
Fatigue Cough Dyspnea Chest pain and tightness Anorexia Nausea Abdominal pain |
OP swab | Chest CT: GGO and consolidation |
Methylprednisolone IVIG Interferon α |
Tacrolimus discontinued MMF discontinued |
Recovered Repeat OP swab negative on day 18 |
44 12 | 38 | Not available |
Fever Cough |
OP swab | Chest CT: typical signs of viral infection | Oseltamivir or arbidol a |
Tacrolimus reduced MMF discontinued |
Recovered Repeat OP swab negative on day 26 |
45 12 | 64 | Bladder cancer |
Fever Productive cough Myalgias Fatigue |
OP swab | Chest CT: typical signs of viral infection | Oseltamivir or arbidol a |
Glucocorticoid discontinued MMF discontinued |
Residual dyspnea at time of hospital discharge |
46 12 | 37 | HTN |
Fever Cough |
OP swab |
Chest CT: typical signs of viral infection |
Oseltamivir or arbidol a IVIG |
Tacrolimus discontinued MMF discontinued |
Recovered Repeat OP swab negative on day 22 |
47 12 | 47 | Not available |
Fever Productive cough Myalgias Fatigue |
OP swab | Chest CT with typical signs of viral infection | Oseltamivir or arbidol a |
Tacrolimus discontinued MMF discontinued Glucocorticoid discontinued |
Resolved Repeat OP swab positive on day 18 |
48 12 | 38 |
HTN DM |
Fever Productive cough Myalgias Fatigue |
OP swab | Chest CT with typical signs of viral infection | Oseltamivir or arbidol a | None |
Resolved Repeat OP swab negative on day 18 |
49 13 | 49 | Not available |
Fever Respiratory symptoms |
NP swab | Chest CT with multifocal GGO |
Lopinavir/ritonavir Ribavirin Interferon‐alpha‐2b Methylprednisolone |
None | Resolved |
50 14 | 58 | Testicular cancer |
Fever Dyspnea Cough |
NP swab | Chest CT peripheral GGO | None | Belatacept discontinued MMF discontinued | Resolved |
Abbreviarions: AKI, acute kidney injury; COPD, chronic obstructive pulmonary disease; CXR, chest radiograph; DM, diabetes mellitus; GGO, ground‐glass opacity; HBV, hepatitis B virus; HTN, hypertension; ITP, idiopathic thrombocytopenic purpura; IVIG, intravenous immunoglobulin; MMF, mycophenolate mofetil; NP, nasopharyngeal; OP, oropharyngeal; PTLD, post‐transplant lymphoproliferative disorder.
Not specified which of the two medications (oseltamivir or arbidol) the patient received.
Imaging modality not specified.