TABLE 2.

Multivariate statistical testing of effects of microbiome on fish health metrics (continuous variables), Adonis 999 permutations^a

Parameter	Metadata name	Unweighted UniFrac						Weighted UniFrac
		Gill		Skin		Gut		Gill		Skin		Gut
		R2	P	R2	P	R2	P	R2	P	R2	P	R2	P
Fish length	host_height	x	0.726	x	0.106		0.569	x	0.116	x	0.051	x	0.873
Fish mass	host_weight	x	1.000	x	1.000		1.000	x	1.000	x	1.000	x	1.000
Fish K factor	sal_k_factor	x	1.000	x	1.000		1.000	x	1.000	x	1.000	x	1.000
Gut histology (fold ht)	sal_histo_gi_fold_height	x	1.000	x	1.000		1.000	x	1.000	x	1.000	x	1.000
Gut histology (mucosa thickness)	sal_histo_gi_mucosa_thickness	x	1.000	x	1.000		1.000	x	1.000	x	1.000	x	1.000
Gut histology (fold width)	sal_histo_gi_fold_width	x	1.000	x	1.000		1.000	x	1.000	x	1.000	x	1.000
Gut histology (muscularis thickness)	sal_histo_gi_muscularis_thickness	x	1.000	x	1.000		1.000	x	1.000	x	1.000	x	1.000
Gut histology (no. of goblet cells)	sal_histo_gi_goblet_cells	x	0.148	x	0.073		0.666	0.936	0.026	0.946	0.014	x	0.294
Gill histology (mucous cells per 0.2 mm2)	sal_histo_gill_mucous_cell_num_gill	x	0.081	0.749	0.025		0.056	x	0.203	x	0.378	x	0.131
Skin histology (mucous cells per 0.2 mm2)	sal_histo_skin_mucous_cell_num_skin	x	0.459	0.905	0.006	0.915	0.015	x	0.369	x	0.142	0.970	0.002
Skin histology (mucous cells per mm2)	sal_histo_skin_mucous_cells_permm2_skin	x	0.424	0.905	0.003	0.915	0.015	x	0.360	x	0.154	0.970	0.002

^ax, not reported.