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. 2020 May 27;11:1019. doi: 10.3389/fimmu.2020.01019

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Copyright © 2020 Bæk, Brunse, Nguyen, Moodley, Thymann and Sangild.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Preterm birth increases susceptibility to Staphylococcus epidermidis bacteremia. Results of Experiment 1 comparing term (TERM) and preterm (PRE) pigs infused with Staphylococcus epidermidis (SE) or saline (CON) immediately after birth, without any enteral feeding. (A) Survival rates 24 h post inoculation. (B) Motor activity, shown as the fraction of time when pigs were physically moving at 2–18 h post inoculation. (C) Body temperature 2–24 h post inoculation. (D) Blood pH 6–24 h post inoculation. (E) Blood lactate levels 6–24 h post inoculation. (A) Presented as Kaplan Meyer curves. (B–E) Presented as means with corresponding standard errors. (#): Effect of SE (p ≤ 0.1 ≥ 0.05), #: Effect of SE (p < 0. 05), ###: Effect of SE (p < 0.001), ¤: Effect of gestational age (p < 0.05).