Table I.
Clinical and biological characteristics of patients diagnosed with haematological disorders.
| Gender (M/F) | Age (years) | Date of diagnosis | Swabs for COVID‐19 testing after diagnosis (number/result) | Diagnosis | Molecular and/or cytogenetics | WBC/μl at baseline | Estimated days of symptoms before going to the emergency room | Symptoms before diagnosis | Comorbidities associated with HL at diagnosis | Follow‐up |
|---|---|---|---|---|---|---|---|---|---|---|
| F | 57 | 03/17/2020 | 2/negative | Blast crisis in chronic myeloid leukaemia |
P190 BCR/ABL t(9;22) |
299 000 | 23 | Weakness, diffuse purpura, conjunctivitis | Acute kidney failure (creatinine value: 8–6 mg/l) | Death after two days of salvage haemodialysis |
| F | 65 | 03/18/2020 | 2/negative | Acute myeloid leukaemia |
NPM1 46XX |
326 000 | 27 | Fever unresponsive to antibiotics, hypoacusia | Infective lung nodule (9 × 5 cm), severe respiratory insufficiency | On induction chemotherapy after 3 weeks of i.v. antibiotics and antifungal therapy |
| M | 71 | 03/22/2020 | 2/negative | Mantle cell lymphoma | t(11;14) | 190 000 | 45 | Low‐grade fever, night sweats, intermittent abdominal pain | Bowel sub‐occlusion, spleen infarction | On chemotherapy after 2 weeks of surgical surveillance |
| M | 74 | 04/03/2020 | 3/negative | Acute lymphoblastic leukaemia | 46XY | 137 000 | 33 | Weakness, persistent low‐grade fever, sore throat | Acute kidney failure (creatinine value: 4·6 mg/l), gram positive sepsis | On induction chemotherapy after 2 weeks of salvage haemodialysis and 2 weeks of i.v. antibiotics |
| M | 65 | 04/09/2020 | 2/negative | Acute myeloid leukaemia |
FLT3 ITD and FLT3 TKD 46XY |
86 000 | 35 | Persistent low‐grade fever, pain on right lower limb associated with initial claudication | Pneumonia, superficial thrombosis of femoral arteries | On treatment with i.v. antibiotics and anticoagulant therapy (chemotherapy not yet started) |
| F | 65 | 04/14/2020 | 3/negative | Acute myeloid leukaemia |
FLT3 ITD and NPM1 46XX |
95 000 | 42 | Fever unresponsive to antibiotics, persistent cough | Interstitial pneumonia | On treatment with i.v. antibiotics (chemotherapy not yet started) |
| F | 63 | 04/20/2020 | 2/negative | Blast crisis in chronic myeloid leukaemia |
P190 BCR/ABL t(9;22); +8 in 4 metaphases |
77 000 | 21 | Fever unresponsive to antibiotics | Pneumonia | On treatment with i.v. antibiotics (chemotherapy not yet started) |
| F | 51 | 04/22/2020 | 2/negative | Accelerated phase in chronic myeloid leukaemia |
P210 BCR/ABL t(9;22) |
175 000 | 33 | Weakness, fever unresponsive to antibiotics | Pneumonia | On treatment with i.v. antibiotics (chemotherapy not yet started) |
M, male; F, female; WBC, white blood cells; HL, hyperleukocytosis; i.v., intravenous.