Table 1.
Comparison of baseline between stable and progressive groups
| Variables | Total | Stable group | Progressive group | P |
|---|---|---|---|---|
| N | 344 | 299 | 45 | |
| Male (%) | 188 (54.7) | 156 (52.2) | 32 (71.1) | .027 |
| Age, y | 52.9 ± 16.8 | 51.6 ± 16.5 | 61.5 ± 16.2 | <.001 |
| Onset time, median (IQR) | 3 (2, 5) | 3 (1, 5) | 5 (3, 7) | .006 |
| Death (%) | 15 (4.4) | 0 (0) | 15 (33.3) | <.001 |
| T ≥ 38.5 (%) | 162 (47.1) | 128 (42.8) | 34 (75.6) | <.001 |
| Current smoker (%) | 56 (16.3) | 47 (15.7) | 9 (20.0) | .611 |
| Heavy drinking (%) | 24 (7.0) | 22 (7.4) | 2 (4.4) | .753 |
| Comorbidity | 108 (31.4) | 80 (26.8) | 28 (62.2) | <.001 |
| Hypertension (%) | 78 (22.7) | 58 (19.4) | 20 (44.4) | <.001 |
| DM (%) | 38 (11.0) | 25 (8.4) | 13 (28.9) | <.001 |
| CHD (%) | 18 (5.2) | 9 (3.0) | 9 (20.0) | <.001 |
| CVD (%) | 9 (2.6) | 6 (2.0) | 3 (6.7) | .1 |
| COPD (%) | 9 (2.6) | 5 (1.7) | 4 (8.9) | .02 |
| Cancer (%) | 9 (2.6) | 5 (1.7) | 4 (8.9) | .02 |
| Fever (%) | 270 (78.5) | 227 (75.9) | 43 (95.6) | .005 |
| Cough (%) | 252 (73.3) | 212 (70.9) | 40 (88.9) | .018 |
| Sputum (%) | 156 (45.3) | 123 (41.1) | 33 (73.3) | <.001 |
| Dyspnea (%) | 39 (11.3) | 15 (5.0) | 24 (53.3) | <.001 |
| Headache (%) | 14 (4.1) | 11 (3.7) | 3 (6.7) | .407 |
| Fatigue (%) | 120 (34.9) | 99 (33.1) | 21 (46.7) | .107 |
| SBP, mm Hg | 127.3 ± 14.6 | 127.3 ± 14.6 | 127.2 ± 14.7 | .939 |
| DBP mm Hg | 77.3 ± 10.9 | 77.2 ± 10.7 | 77.9 ± 12.3 | .732 |
| HR, rates/min | 87.8 ± 10.8 | 87.8 ± 10.8 | 87.8 ± 11 | .987 |
| RR, rates/min | 21.7 ± 2.4 | 21.7 ± 2.3 | 21.9 ± 3.4 | .628 |
| WBC, ×109/L | 4.8 ± 2.1 | 4.6 ± 1.9 | 5.7 ± 3.1 | .027 |
| Neutrophil, ×109/L | 3.2 ± 2 | 3 ± 1.7 | 4.7 ± 3.3 | <.001 |
| Lymphocyte, ×109/L | 1.2 ± 0.5 | 1.2 ± 0.5 | 0.9 ± 0.4 | <.001 |
| NLR | 3.5 ± 4.5 | 2.9 ± 2.3 | 7.9 ± 10.1 | .002 |
| Monocyte, ×109/L | 0.3 ± 0.2 | 0.3 ± 0.2 | 0.3 ± 0.1 | .225 |
| CRP, mg/L | 24.4 ± 33 | 21.2 ± 31.1 | 44.7 ± 37.7 | <.001 |
| Procalcitonin, μg/L | 0.1 ± 0.5 | 0.1 ± 0.5 | 0.2 ± 0.3 | .258 |
| ESR, mm/h | 35.5 ± 25.9 | 33.1 ± 24.5 | 49.8 ± 29.5 | <.001 |
| FIB, g/L | 3.2 ± 1.0 | 3.2 ± 1 | 3.5 ± 0.9 | .106 |
| D‐dimer, mg/L | 1.2 ± 3.0 | 1.0 ± 1.9 | 2.5 ± 6.5 | .13 |
| TBIL, μmol/L | 11.1 ± 6.5 | 11.1 ± 6.7 | 11.1 ± 4.8 | .96 |
| Albumin, g/L | 37.7 ± 5.9 | 38.3 ± 5.8 | 33.5 ± 4.8 | <.001 |
| LDH, U/L | 234.9 ± 135.3 | 217.1 ± 108 | 339.2 ± 212.9 | <.001 |
| ALT, U/L | 27.4 ± 21.5 | 26.9 ± 20.8 | 30.8 ± 25.8 | .342 |
| AST, U/L | 25.3 ± 17.2 | 24.1 ± 16.7 | 32.6 ± 18.7 | .006 |
| Creatinine, μmolL | 74.6 ± 44.6 | 70.1 ± 24.0 | 103.8 ± 101.6 | .032 |
Note: Continuous variables were expressed as means ± SD or medians with interquartile ranges (IQRs).
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; CHD, coronary heart disease; COPD, chronic obstructive pulmonary disease; CRP, C‐reactive protein; CVD, cerebrovascular disease; DBP, diastolic pressure; DM, diabetes mellitus; ESR, erythrocyte sedimentation rate; HR, heart rate; ICU, intensive care unit; LDH, lactic dehydrogenase; NLR, Neutrophil‐to‐lymphocyte ratio; RR, respiratory rate; SBP, systolic pressure; WBC, white blood cell count.