Table 1.
Parameters | Findings | |||||||
---|---|---|---|---|---|---|---|---|
Study | Chen et al 2 | Zhu et al 3 | Liu et al 4 | Zeng et al 5 | Zhang et al 6 | Chen et al 7 | Liu et al 8 | Li et al 9 |
Study period | 20.1.20‐31.1.20 | 20.1.20‐5.2.20 | 8.12.19‐5.2.20 | Jan‐Feb | 30.01.20‐17.02.20 | 30.01.20‐23.2.20 | 20.1.20‐ 10.2.20 | 24.1.20‐ 29.2.20 |
Confirmed SARS‐CoV‐2+ pregnant women | 9 | 9 | 13 | 33 | 16 | 17 | 15 | 16 |
Time point of symptom presentation | ||||||||
1st trimester | 0 | 0 | 0 | NR | 0 | NR | 1 | 0 |
2nd trimester | 0 | 0 | 2 | NR | 0 | NR | 2 | 0 |
3rd trimester (before birth) | 9 | 6 | 11 | NR | 16 | NR | 12 | 4 |
After delivery | 0 | 3 | 0 | NR | 0 | NR | 0 | 8 |
Maternal morbidity with COVID‐19 | ||||||||
Asymptomatic | 0 | 0 | 1 | NR | NR | 9 | 2 | 4 |
Symptomatic | 9 | 9 | 11 | NR | NR | 8 | 13 | 12 |
Severe | 0 | 0 | 1 | NR | 1 | 0 | 0 | 0 |
Total number that delivered | 9 | 9 | 13 | 33 | 16 | 17 | 11 | 16 |
Cesarean delivery | 9 | 7 | 5 | 26 | 16 | 17 | 10 | 14 |
Pregnancy outcome | ||||||||
Miscarriage | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Preterm delivery | 4 | 5 | 6 | 4 | 1 | 3 | 3 | 4 |
Term delivery | 5 | 4 | 6 | 29 | 15 | 14 | 8 | 12 |
Recovered without delivering | 0 | 0 | 0 | 0 | 0 | 0 | NR | 0 |
Maternal mortality | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Number of neonates included in study | 9 | 10 | 13 | 33 | 10 | 17 | 11 | 17 |
Neonatal adverse outcome | ||||||||
Pneumonia | 0 | 4 | NR | 3 | 3 (bacterial) | 0 | NR | NR |
Low birthweight | 2 | 6 | NR | NR | NR | 0 | NR | 3 |
SGA | NR | 2 | NR | 3 | NR | NR | NR | NR |
NRDS | 0 | 2 | NR | 4 | 0 | 0 | NR | 0 |
Preterm neonatal adverse outcome | ||||||||
Pneumonia | 0 | 2/6 | NR | 1/4 | NR | 0 | NR | NR |
Low birthweight | 2/4 | 6/6 | NR | NR | NR | 0/3 | NR | NR |
SGA | NR | 0 | NR | NR | NR | NR | NR | NR |
NRDS | 0 | 0 | NR | NR | NR | 0 | NR | NR |
Neonatal death | 0 | 1/6 | 1/6 | 0 | 0 | 0 | 0 | 0 |
Confirmed SARS‐CoV‐2+ neonates | 0 | 0 | 0 | 3 | 0 | 0 | NR | 0 |
Vertical transmission reported | 0 | a | 0 | a | 0 | 0 | NR | 0 |
Horizontal transmission reported | 0 | 0 | 0 | 3 | 0 | 0 | NR | 0 |
Symptomatic | 0 | 0 | 0 | 3 | 0 | 0 | NR | 0 |
Newborn mortality | 0 | 1/10 | 1/13 | 0 | 0 | 0 | 0 | 0 |
Abbreviations: COVID, coronavirus disease; NR, not reported; NRDS, neonatal respiratory distress syndrome; SARS‐CoV‐2, severe acute respiratory syndrome‐coronavirus 2; SGA, small for gestational age.
Vertical transmission not ruled out.