Table I.

Characteristics of seven patients with autoimmune haemolytic anaemia after the onset of COVID‐19.

Patient	Age	Gender	Comorbidity	CT‐scan*	Oropharyngeal swab (tested by PCR)	Haemoglobin (g/l)	Reticulocyte count (109/l)	Lymphocyte count (109/l)	Lactate dehydrogenase (U/l)	Haptoglobin (g/l)	DAT specificity	Optimum temperature	Day between COVID‐19 symptoms and AIHA	Related pathology	AIHA treatment	Response
#1	61	M	Hypertension, chronic renal failure	Moderate	Positive	60	477	250	1000	<0·1	IgG + C3d	warm	13	CLL	Steroids	Ongoing
#2	89	F	Hypertension, chronic renal failure, atrial fibrillation	Mild	Positive	84	103	1·7	598	<0·1	IgG + C3d	warm	7	MGUS	Steroids	Ongoing
#3	62	F	Hypertension, cirrhosis	Severe	Positive	108	101	1·3	357	<0·1	C3d	cold	4	MZL†	1. Steroids 2. Rituximab	PR Planed
#4	69	F	Obesity	Moderate	Positive	38	215	5·9	2610	<0·1	IgG + C3d	cold	10	MZL	Steroids	PR
#5	61	M	Hypertension, chronic renal failure, diabetes, hypercholesterolaemia	Mild	Positive	72	145	3	807	0·8	C3d	cold	11	Prostate cancer	RBC infusion	Ongoing
#6	61	M	Diabetes	Severe	Positive	70	155	1·2	1800	<0·1	IgG	warm	9	None	1. Steroids 2. Rituximab‡	Failure Ongoing
#7	75	M	Diabetes, hypercholesterolaemia, cardiopathy, obesity, chronic obstructive bronchopneumopathy	Moderate	Positive	71	98	108	2000	<0·1	IgG	warm	6	CLL	RBC infusion	Ongoing

CT, computed tomography; PCR, polymerase chain reaction; DAT, direct antiglobulin test; AIHA, autoimmune haemolytic anaemia; CLL, chronic lymphocytic leukaemia; MGUS, monoclonal gammopathy of undetermined significance; MZL, marginal zone lymphoma; RBC, red blood cells; PR, partial response.

^*Degree of involvement of the lung was classified as none (0%), minimal (1–25%), mild (26–50%), moderate (51–75%), or severe (76–100%).

^†MZL B cell clone was detected in the bone marrow.

^‡Patient 6 received rituximab injection because of corticosteroid failure.